Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan
Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan
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DOI：
10.1111/j.1440-1746.2004.03521.x
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发表时间：
2005-01-01
影响因子：
4.1
通讯作者：
Arakawa, T
中科院分区：
文献类型：
--
作者：
Fujiwara, Y;Higuchi, K;Arakawa, T
背景和目的：流行病学研究表明，发达国家10 - 48%的人有胃食管反流病（GERD）症状，如烧心和反酸。本研究旨在探讨GERD症状和GERD在日本subjects.Methods的患病率：一个横断面研究的日本受试者谁访问了诊所进行常规健康检查了。受试者被要求填写一份自我报告问卷。胃食管反流病的定义是每周至少有两次胃灼热和/或反酸。（44.1%）报告在过去一年中有胃灼热和/或反酸：每日1次124例（2.1%），每周2次275例（4.6%），每月2次773例（12.8%），每月少于2次1490例（24.7%）。399例（6.6%）受试者被诊断为GERD，GERD的患病率与性别或年龄无关。令人烦恼的胃食管反流病症状的患病率显着高于在没有GERD.Conclusion：约6.6%的日本人有胃食管反流病和大多数人胃食管反流病胃灼热或酸反流作为麻烦。(C)2005年Blackwell Publishing Asia Pty Ltd.
Background and Aim: Epidemiological studies have shown that 10-48% of people in developed countries have gastroesophageal reflux disease (GERD) symptoms such as heartburn and acid regurgitation. The present study aimed to examine the prevalence of GERD symptoms and GERD in Japanese subjects.Methods: A cross-sectional study of Japanese subjects who visited a clinic for a routine health check up was carried out. Subjects were asked to fill out a self-report questionnaire. GERD was defined as the presence of heartburn and/or acid regurgitation at least twice per week.Results: Of the 6035 eligible subjects, 2662 (44.1%) reported having had heartburn and/or acid regurgitation during the past year: 124 (2.1%) daily, 275 (4.6%) twice per week, 773 (12.8%) twice per month and 1490 (24.7%) less than twice per month. Three hundred and ninety-nine (6.6%) subjects were diagnosed as having GERD and there was no relationship between the prevalence of GERD and either sex or age. The prevalence of bothersome GERD symptoms was significantly higher in subjects with GERD than in those without GERD.Conclusion: Approximately 6.6% of Japanese have GERD and most persons with GERD described heartburn or acid regurgitation as bothersome. (C) 2005 Blackwell Publishing Asia Pty Ltd.