Surface acoustic wave based pumping in a microchannel
Surface acoustic wave based pumping in a microchannel
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DOI：
10.1007/s00542-016-2880-9
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发表时间：
2016-02
期刊：
影响因子：
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通讯作者：
Tao Wang;Qi Ni;N. Crane;R. Guldiken
中科院分区：
文献类型：
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作者：
Tao Wang;Qi Ni;N. Crane;R. Guldiken
微流控通道中液体的泵送和操纵在许多机械、化学和生物医学应用中具有重要意义。基于高效率压电衬底的表面声波器件最近被研究用于微流控通道中的混合和分离。本文介绍了一种用于微通道内液体输送和精确操纵的新型集成声表面波泵。该器件在器件设计中采用了疏水表面涂层(Cytop)，以减少摩擦力，增加粘合力。与以往大多数基于灌装和吸入过程的表面声波泵不同，我们展示了远距离介质输送(高达8 mm)和高抽速，增加了该装置的应用空间和批量生产潜力。此外，器件设计不需要基板和通道之间精确的水层和玻璃层，大大简化了设计。在这项研究中，我们进行了广泛的参数研究，量化了泵浦液体体积、微通道尺寸、输入功率以及疏水表面涂层的存在对泵浦速度和泵浦性能的影响。结果表明，在输入功率相同的情况下，在较薄的微通道(250和500µm)中采用疏水表面涂层(Cytop)可以使恒定液体体积的泵浦速度提高130%(2.31vs0.99 mm/min)。该设备可用于需要小规模精确液体控制和输送的循环、定量、计量和药物输送应用。
Pumping and manipulation of liquids in microfluidic channels are important for many mechanical, chemical and biomedical applications. Surface acoustic wave based devices fabricated on high-efficiency piezoelectric substrates have been recently investigated for mixing and separation application within microfluidic channels. In this paper, we introduce a novel integrated surface acoustic wave based pump for liquid delivery and precise manipulation within a microchannel. The device employs a hydrophobic surface coating (Cytop) in the device design to decrease the friction force and increase the bonding. Contrary to previous surface acoustic wave based pumps which were mostly based on the filling and sucking process, we demonstrate long distance media delivery (up to 8 mm) and high pumping velocity increasing the device’s application space and mass production potential. Additionally, the device design does not need precise layers of water and glass between substrate and channel, simplifying the design significantly. In this study, we conducted extensive parametric studies to quantify the effects of the liquid volume pumped, microchannel size, input applied power as well as the existence of hydrophobic surface coating on the pumping velocity and pump performance. Our results indicate that the pumping velocity for a constant liquid volume with the same applied input power can be increased by over 130 % (2.31 vs 0.99 mm/min) by employing a hydrophobic surface coating (Cytop) in a thinner microchannel (250 vs 500 µm) design. This device can be used in circulation, dosing, metering and drug delivery applications which necessitates small-scale precise liquid control and delivery.