Perceived social support in patients with chronic pain with and without opioid use disorder and role of medication for opioid use disorder.
Perceived social support in patients with chronic pain with and without opioid use disorder and role of medication for opioid use disorder.
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DOI：
10.1016/j.drugalcdep.2021.108619
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发表时间：
2021-04-01
影响因子：
4.2
通讯作者：
Cheatle MD
中科院分区：
文献类型：
--
作者：
Benville JR;Compton P;Giordano NA;Cheatle MD
慢性非癌性疼痛（CNCP）和阿片类药物使用障碍（OUD）患者治疗结果的一个重要预测因素是他们获得的社会支持的程度和质量。具体而言，在CNCP和长期阿片类药物治疗的患者中，OUD的发展往往与社会支持的丧失有关，而参与OUD治疗可以改善支持网络。提供循证OUD治疗药物，美沙酮和丁丙诺啡，发生在临床环境中，明显不同的社会支持资源。本研究的目的是描述CNCP患者的感知社会支持无OUD（无OUD），与OUD和丁丙诺啡（OUD-BP），与OUD和美沙酮（OUD-美沙酮）。使用杜克社会支持指数（DSSI），在无OUD（n = 834）、OUD-美沙酮（n=83）和OUD-BP（n=99）治疗的CNCP和阿片类药物治疗的白人患者样本中比较感知的社会支持。平均DSSI得分进行了比较，各组和线性回归模型计算，以描述组和感知社会支持之间的关联。在无OUD和OUD-美沙酮之间没有观察到DSSI评分的差异，但是OUD-BP参与者的评分低于接受美沙酮（x = −5.2，95%CI：−7.5，−2.9）和无OUD（x = −6.5，95%CI：−8.2，−4.9）的参与者。接受美沙酮治疗的CNCP和OUD患者的社会支持水平与未接受OUD的患者相当，但接受丁丙诺啡治疗的患者报告的支持显著减少，这对OUD治疗结果产生了影响。
A significant predictor of treatment outcomes for patients with chronic non-cancer pain (CNCP) and opioid use disorder (OUD) is the degree and quality of social support they receive. Specifically, in patients with CNCP and on long-term opioid therapy, the development of OUD tends to be associated with losses in social support, while engagement in treatment for OUD improves support networks. Delivery of the evidence-based OUD treatment medications, methadone and buprenorphine, occurs in clinical environments which patently differ with respect to social support resources. The aims of this study were to describe perceived social support in patients with CNCP without OUD (no-OUD), with OUD and on buprenorphine (OUD-BP), and with OUD and on methadone (OUD-methadone). Using the Duke Social Support Index (DSSI), perceived social support in a sample of Caucasian patients with CNCP and on opioid therapy was compared between no-OUDs (n = 834), OUD-methadone (n=83) and OUD-BP (n=99) therapy. Average DSSI scores were compared across groups and a linear regression model computed to describe association between group and perceived social support. No difference was observed in DSSI scores between no-OUDs and OUD-methadone, however scores were lower among OUD-BP participants than those receiving methadone (x = −5.2, 95% CI: −7.5, −2.9) and no-OUDs (x = −6.5, 95% CI: −8.2, −4.9). Patients with CNCP and OUD on methadone therapy endorse levels of social support comparable to those without OUD, however those on buprenorphine therapy report significantly less support, bringing implications for OUD treatment outcomes.
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影响因子：
4
作者：
Fillingim, Roger B.;Bruehl, Stephen;Dworkin, Robert H.;Dworkin, Samuel F.;Loeser, John D.;Turk, Dennis C.;Widerstrom-Noga, Eva;Arnold, Lesley;Bennett, Robert;Edwards, Robert R.;Freeman, Roy;Gewandter, Jennifer;Hertz, Sharon;Hochberg, Marc;Krane, Elliot;Mantyh, Patrick W.;Markman, John;Neogi, Tuhina;Ohrbach, Richard;Paice, Judith A.;Porreca, Frank;Rappaport, Bob A.;Smith, Shannon M.;Smith, Thomas J.;Sullivan, Mark D.;Verne, G. Nicholas;Wasan, Ajay D.;Wesselmann, Ursula
通讯作者：
Wesselmann, Ursula
影响因子：
105.7
作者：
FARRELL, M;WARD, J;STRANG, J
通讯作者：
STRANG, J
影响因子：
158.5
作者：
Fiellin, David A.;Pantalon, Michael V.;Schottenfeld, Richard S.
通讯作者：
Schottenfeld, Richard S.
影响因子：
3.1
作者：
GOSSOP, M;GREEN, L;BRADLEY, B
通讯作者：
BRADLEY, B
影响因子：
5.9
作者：
Cheatle, Martin D.
通讯作者：
Cheatle, Martin D.