Effects of age and inactivity due to prolonged bed rest on atrophy of trunk muscles
Effects of age and inactivity due to prolonged bed rest on atrophy of trunk muscles
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DOI：
10.1007/s00421-011-1952-x
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发表时间：
2012-01-01
影响因子：
3
通讯作者：
Ichihashi, Noriaki
中科院分区：
文献类型：
--
作者：
Ikezoe, Tome;Mori, Natsuko;Ichihashi, Noriaki
本研究调查了年龄和长期卧床不起导致的不活动对躯干肌肉萎缩的影响。研究对象包括33名年轻女性（年轻组）和41名居住在疗养院或慢性护理机构的老年女性。将老年受试者分为两组：能够进行日常生活活动（包括独立行走）的独立老年组（n = 28）和慢性卧床不起的依赖老年组（n = 13）。采用B超测量腹直肌、腹外斜肌、腹内斜肌、腹横肌、胸竖脊肌（最长肌）和腰多裂肌等6块躯干肌的厚度。与年轻组相比，独立老年组除腹横肌和腰多裂肌外，其他肌肉均显着变薄。老年依赖组各肌层厚度均显著小于青年组，而腹直肌和内斜肌厚度无显著差异。总之，我们的研究结果表明：（1）与年轻女性相比，独立老年女性的深层抗重力躯干肌肉的年龄相关性萎缩程度低于浅层肌肉;（2）与长期卧床休息相关的萎缩在抗重力肌肉中更为明显，如背部和腹横肌。
This study investigated the effects of age and inactivity due to being chronically bedridden on atrophy of trunk muscles. The subjects comprised 33 young women (young group) and 41 elderly women who resided in nursing homes or chronic care institutions. The elderly subjects were divided into two groups: independent elderly group who were able to perform activities of daily living involving walking independently (n = 28) and dependent elderly group who were chronically bedridden (n = 13). The thickness of the following six trunk muscles was measured by B-mode ultrasound: the rectus abdominis, external oblique, internal oblique, transversus abdominis, thoracic erector spinae (longissimus) and lumbar multifidus muscles. All muscles except for the transversus abdominis and lumbar multifidus muscles were significantly thinner in the independent elderly group compared with those in the young group. The thicknesses of all muscles in the dependent elderly group was significantly smaller than that in the young group, whereas there were no differences between the dependent elderly and independent elderly groups in the muscle thicknesses of the rectus abdominis and internal oblique muscles. In conclusion, our results suggest that: (1) age-related atrophy compared with young women was less in the deep antigravity trunk muscles than the superficial muscles in the independent elderly women; (2) atrophy associated with chronic bed rest was more marked in the antigravity muscles, such as the back and transversus abdominis.