High Prevalence of Human Parechovirus (HPeV) Genotypes in the Amsterdam Region and Identification of Specific HPeV Variants by Direct Genotyping of Stool Samples
High Prevalence of Human Parechovirus (HPeV) Genotypes in the Amsterdam Region and Identification of Specific HPeV Variants by Direct Genotyping of Stool Samples
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DOI：
10.1128/jcm.01379-08
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发表时间：
2008-12-01
影响因子：
9.4
通讯作者：
Wolthers, K.
中科院分区：
文献类型：
--
作者：
Benschop, K.;Thomas, X.;Wolthers, K.
人类双埃柯病毒（HPeV）是属于小核糖核酸病毒科的广泛分布的病原体。已知有六种基因型，主要从儿童中分离出来。关于HPeV基因型流行率的数据通常基于细胞培养，这可能低估了某些难以生长的HPeV毒株的流行率。我们研究了来自1,379名儿童的1,824份粪便样本（
Human parechoviruses (HPeV) are widespread pathogens belonging to the Picornavirus family. Six genotypes, which have predominantly been isolated from children, are known. Data on prevalence of HPeV genotypes are generally based on cell culture, which may underestimate the prevalence of certain HPeV strains that are difficult to grow. We studied 1,824 stool samples from 1,379 children (