Self-replication: spelling it out in a chemical background
Self-replication: spelling it out in a chemical background
复制标题
自我复制:在化学背景下拼出它
DOI:
10.1007/s12064-010-0117-5
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发表时间:
2011-06
影响因子:
1.1
通讯作者:
Zhou, Ping
中科院分区:
文献类型:
--
作者:
Yu, Chunwu;Hu, Jiming;Ma, Wentao;Zhang, Wentao;Zhou, Ping
Self-replication, an important concept abstracted from reproduction, the key feature of life, remains vague in definition and lacking in clear interpretation in terms of its chemical mechanism. Mentioned frequently in discussions concerning the essence of life and its origin, the vague concept has caused a lot of uncertain statements, confusable references, and malposed debates, and has seriously held back efforts in this field. In this article, we try to improve the situation by a conceptual analysis in a more fundamental and clearer background. Self-replication in the substantial world could not mean anything but that “an entity favors the production of its own.” The major chemical mechanism for such favoring is catalysis, which can be classified into speed- and direction-favoring types (the template-directing function is actually a type of direction-favoring catalysis). Molecular self-replication could be based on autocatalysis or self-metabolism; the self-replication of a complex entity could be based on autocatalytic and/or self-metabolic sets, and should involve a mechanism of self-division. This conceptual clarification sheds light on the dim areas concerning the essence of life and its origin.
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影响因子:
4.4
作者:
M. Eigen;P. Schuster
通讯作者:
M. Eigen;P. Schuster
DOI:
10.1101/087969380.24.1
发表时间:
1993
期刊:
Cold Spring Harbor Monograph Archive
影响因子:
--
作者:
G. F. Joyce;L. Orgel
通讯作者:
G. F. Joyce;L. Orgel
影响因子:
64.8
作者:
T. Cech
通讯作者:
T. Cech
影响因子:
1.2
作者:
Kozlov, IA;Orgel, LE
通讯作者:
Orgel, LE
DOI:
10.3891/acta.chem.scand.50-0469
发表时间:
1996
期刊:
Acta Chemica Scandinavica
影响因子:
--
作者:
E. Wintner;J. Rebek;B. Pilawa;G. Jensen;Inge L. Møller;Ruby I. Nielsen;C. Olsen;C. N. Rosendahl;M. Haugg;N. Trabesinger-Rüf;E. Weinhold
通讯作者:
E. Wintner;J. Rebek;B. Pilawa;G. Jensen;Inge L. Møller;Ruby I. Nielsen;C. Olsen;C. N. Rosendahl;M. Haugg;N. Trabesinger-Rüf;E. Weinhold