Chemically Fuelled Plasmon Switching of Gold Nanorods by Single Base Pairing of Surface-Grafted DNA.
Chemically Fuelled Plasmon Switching of Gold Nanorods by Single Base Pairing of Surface-Grafted DNA.
复制标题
通过表面接枝 DNA 的单碱基配对化学燃料等离子体激元开关金纳米棒。
作者：
Lan Zhang;Chenlin Zhao;Yao Zhang;Luyang Wang;Guoqing Wang;N. Kanayama;T. Takarada;M. Maeda;Xingguo Liang
金属离子和生物分子之间的相互作用对于各种生物过程至关重要。利用这些分子相互作用的等离子体开关纳米器件的开发具有基础和技术意义。在这里，我们展示了基于双链 DNA 修饰金纳米棒 (dsDNA-AuNR) 快速聚集/分散的等离子体开关，其表现出取决于末端碱基配对/不配对的胶体行为。在倒数第二个位置具有胸腺嘧啶-胸腺嘧啶 (T-T) 错配的 dsDNA-AuNR 在 Hg2+ 存在下，由于 T-Hg-T 碱基配对，会发生自发的非交联聚集。相反，随后添加半胱氨酸 (Cys) 会导致从 T-Hg-T 碱基对中去除 Hg2+，从而重现 T-T 错配，从而导致 dsDNA-AuNR 稳定分散。化学响应等离子体开关允许在室温下快速且可重复的循环。通过在 dsDNA-AuNR 中安装 Ag+ 结合 DNA 序列，开发另一种由 Ag+ 和 Cys 驱动的等离子体开关，进一步证明了本方法的有效性。
The interactions between metal ions and biomolecules are crucial to various bioprocesses. Development of plasmonic switching nanodevices that exploit these molecular interactions is of fundamental and technological interest. Here we show plasmonic switching based on rapid aggregation/dispersion of double-stranded DNA-modified gold nanorods (dsDNA-AuNRs) that exhibit the colloidal behaviours depending on pairing/unpairing of the terminal bases. The dsDNA-AuNRs bearing a thymine-thymine (T-T) mismatch at the penultimate position undergo spontaneous non-cross-linking aggregation in the presence of Hg2+ due to T-Hg-T base pairing. Inversely, the subsequent addition of cysteine (Cys) gives rise to removal of Hg2+ from the T-Hg-T base pair to reproduce the T-T mismatch, resulting in stable dispersion of the dsDNA-AuNRs. The chemical-responsive plasmonic switch allows for the rapid and repeatable cycles at room temperature. The validity of present method is further exemplified by developing another plasmonic switch fuelled by Ag+ and Cys by installing the Ag+-binding DNA sequence in the dsDNA-AuNR.
影响因子：
7.4
作者：
Demers, LM;Mirkin, CA;Viswanadham, G
通讯作者：
Viswanadham, G
影响因子：
15
作者：
Hall, W. Paige;Anker, Jeffrey N.;Van Duyne, Richard P.
通讯作者：
Van Duyne, Richard P.