Stimulation of neural cells by lateral layer-by-layer films of single-walled currents in conductive carbon nanotubes

Stimulation of neural cells by lateral layer-by-layer films of single-walled currents in conductive carbon nanotubes
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DOI:
10.1002/adma.200600878
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发表时间:
2006-11-17
期刊:
影响因子:
29.4
通讯作者:
Kotov, Nicholas A.
Kotov, Nicholas A.
中科院分区:
材料科学1区
文献类型:
--
作者:
Gheith, Mithammed K.;Pappas, Todd C.;Kotov, Nicholas A.

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描述了通过逐层沉积组装的 SWNT 材料进行神经刺激的第一个示例(见图)。纳米管涂层中横向电流的激发导致电压依赖性Na'离子通道的打开。实验观察结果表明,利用单壁碳纳米管/聚合物多层材料设计可植入生物医学设备,用于神经元假体、疼痛管理和肌肉刺激的可能性。
The first example of neural stimulation through a SWNT material assembled by layer-by-layer deposition is described (see figure). Excitation by lateral currents in the nanotube coating results in the opening of voltage -dependent Na' ion channels. The experimental observations indicate the possibility of engineering of implantable biomedical devices from SWNT/polymer multilayers to be used for neuron prosthesis, pain management, and muscle stimulation.