The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors.
The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors.
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DOI：
10.1001/archotol.1993.01880140038006
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发表时间：
1993-02
期刊：
影响因子：
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通讯作者：
George A. Gates;J. Cobb;R. D’Agostino;P. Wolf
中科院分区：
文献类型：
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作者：
George A. Gates;J. Cobb;R. D’Agostino;P. Wolf
老年性听力损失（老年性耳聋）是老年人的一个重要问题。为了探讨老年性耳聋与心血管疾病（CVD）的可能关系，对1662名老年男性和女性的听力状况进行了测定，并与他们30年的心血管疾病患病率进行了比较。采用经t检验调整的多变量logistic回归计算优势比（OR）和95%置信区间（95% CI），以分别描述676名男性和996名女性的听力与心血管疾病事件、心血管疾病危险因素以及事件和危险因素的关系。心血管疾病事件是冠心病、卒中和间歇性跛行的总和。研究了五组风险因素：高血压和血压;糖尿病、葡萄糖耐受不良和血糖水平;吸烟状况和吸烟包年数;相对体重;和血脂水平，包括胆固醇、甘油三酯和脂蛋白组分。低频听力（低纯音平均值，0.25至1.0 kHz）与心血管疾病事件有关，在两种性别中，但在女性中更多。对于女性，对于40 dB的低纯音平均听力水平，发生任何心血管疾病事件的OR为3.06（95% CI，1.84至5.10）;对于40 dB的高纯音平均听力水平（平均4至8 kHz），发生任何心血管疾病事件的OR为1.75（95% CI，1.28至2.40）。在纯音平均听力水平为40 dB的男性中，中风的OR为3.46（95%CI，1.60至7.45），冠心病的OR为1.68（95%CI，1.10至2.57）。（250字处删节）
Hearing loss with age (presbycusis) is a substantial problem for the elderly. To investigate the possible relation of presbycusis to cardiovascular disease (CVD), the hearing status of a cohort of 1662 elderly men and women was determined and compared with their 30-year prevalence of cardiovascular disease. Age-adjusted multivariate logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) to describe the relation of hearing to cardiovascular disease events, cardiovascular disease risk factors, and both events and risk factors separately for the 676 men and for the 996 women. Cardiovascular disease events were the sum of coronary heart disease, stroke, and intermittent claudication. Five groups of risk factors were studied: hypertension and blood pressure; diabetes, glucose intolerance, and blood glucose level; smoking status and number of pack-years of cigarettes; relative weight; and serum lipid levels, including cholesterol, triglycerides, and lipoprotein fractions. Low-frequency hearing (low pure-tone average, 0.25 to 1.0 kHz) was related to cardiovascular disease events in both genders but more in the women. For women, the OR of having any cardiovascular disease event for a low pure-tone average of 40 dB hearing level was 3.06 (95% CI, 1.84 to 5.10); for a high pure-tone average (average of 4 to 8 kHz) of 40-dB hearing level, the OR for any cardiovascular disease event was 1.75 (95% CI, 1.28 to 2.40). In men with a low pure tone average of 40-dB hearing level, the OR for stroke was 3.46 (95% CI, 1.60 to 7.45) and for coronary heart disease the OR was 1.68 (95% CI, 1.10 to 2.57).(ABSTRACT TRUNCATED AT 250 WORDS)