Plasmids of Diverse Inc Groups Disseminate the Fosfomycin Resistance Gene fosA3 among Escherichia coli Isolates from Pigs, Chickens, and Dairy Cows in Northeast China
Plasmids of Diverse Inc Groups Disseminate the Fosfomycin Resistance Gene fosA3 among Escherichia coli Isolates from Pigs, Chickens, and Dairy Cows in Northeast China
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DOI：
10.1128/aac.00859-17
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发表时间：
2017-07
影响因子：
4.9
通讯作者：
Xiu-Mei Wang;Zhimin Dong;S. Schwarz;Yao Zhu;Xin Hua;Yanhe Zhang;Siguo Liu;Wanjiang Zhang
中科院分区：
文献类型：
--
作者：
Xiu-Mei Wang;Zhimin Dong;S. Schwarz;Yao Zhu;Xin Hua;Yanhe Zhang;Siguo Liu;Wanjiang Zhang
摘要2015年6月至2016年4月期间，从中国东北四省的猪、鸡、奶牛和工作人员中获得了39株携带fosA 3的磷霉素耐药大肠杆菌分离株。将fosA 3基因与blaCTX-M基因共定位在不相容性组IncN（n = 12）、IncN-F33：A-：B-（n = 2）、IncF 33：A-：B-（n = 14）、IncF 14：A-：B-（n = 2）和IncI 1/序列类型136（ST 136）（n = 9）的接合质粒上。在39株大肠杆菌中检测到4种不同的fosA 3基因的遗传背景。大肠杆菌分离株。三种潜在的流行性质粒在E.大肠杆菌菌株。
ABSTRACT Thirty-nine fosfomycin-resistant Escherichia coli isolates carrying fosA3 were obtained from pigs, chickens, dairy cows, and staff in four northeastern provinces of China between June 2015 and April 2016. The fosA3 gene was colocated with blaCTX-M genes on conjugative plasmids of the incompatibility groups IncN (n = 12), IncN-F33:A−:B−(n = 2), IncF33:A−:B−(n = 14), IncF14:A−:B−(n = 2), and IncI1/sequence type 136 (ST136) (n = 9). Four different genetic contexts of fosA3 were detected among the 39 E. coli isolates. Three potential epidemic plasmids circulated among E. coli strains from this region.