Postchallenge hyperglycemia and mortality in a national sample of US adults

Postchallenge hyperglycemia and mortality in a national sample of US adults
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DOI:
10.2337/diacare.24.8.1397
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发表时间:
2001-08-01
期刊:
影响因子:
16.2
通讯作者:
Brancati, FL
Brancati, FL
中科院分区:
医学1区
文献类型:
--
作者:
Saydah, SH;Miret, M;Brancati, FL

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目的-尽管攻毒后高血糖是2型糖尿病的一个公认特征,但其与死亡风险的关系尚不确定。因此,本研究的目的是评估空腹和2小时血糖水平与全因和心血管疾病(CVD)死亡率的独立相关性。(NHANES 11)死亡率研究,一项针对NHANES 11中检查的美国成年人的前瞻性队列研究,重点关注3,092名年龄在30-74岁的成年人接受了口服葡萄糖耐量试验。基线(1976-1980年)。从1976年至1992年的美国国家死亡率文件中确定死亡人数,为了解释复杂的调查设计,我们使用SUDAAN统计软件进行加权分析。
OBJECTIVE - Although postchallenge hyperglycemia is a well-established feature of type 2 diabetes, its association with risk of mortality is uncertain. Therefore, the aim of this study was, to assess the independent association of fasting and 2-h glucose levels with all-cause and cardiovascular disease (CVD) mortality.RESEARCH DESIGN AND METHODS - We analyzed data from the Second National Health and Nutrition Examination Survey (NHANES 11) Mortality Study, a prospective cohort study of U.S. adults examined in the NHANES 11, and focused on the 3,092 adults aged 30-74 years who underwent an oral glucose tolerance test at. baseline (1976-1980). Deaths were identified from U.S. national mortality files from 1976 to 1992, To account for the complex survey design, we used SUDAAN statistical software for weighted analysis.RESULTS - Compared with their normoglycemic counterparts (fasting glucose [FG]