Relationship of leisure-time physical activity and mortality - The Finnish Twin Cohort
Relationship of leisure-time physical activity and mortality - The Finnish Twin Cohort
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DOI：
10.1001/jama.279.6.440
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发表时间：
1998-02-11
影响因子：
120.7
通讯作者：
Koskenvuo, M
中科院分区：
文献类型：
--
作者：
Kujala, UM;Kaprio, J;Koskenvuo, M
背景。-体育活动和健身被认为可以降低过早死亡率，但遗传因素是否会改变这种影响尚不清楚。调查休闲体育活动和死亡率与儿童时期健康习惯的家庭聚集性以及可能使某些人达到更高健康水平的因素。设计。-前瞻性双胞胎队列研究。设置。芬兰.主题-在1975年，在基线，7925名健康男性和7977名健康女性的芬兰双胞胎队列年龄在25至64岁谁回答了问卷调查的身体活动习惯和已知的预测死亡率。那些报告每月至少锻炼6次，强度至少相当于剧烈步行平均持续时间为30分钟的人被归类为条件锻炼者，那些报告没有休闲体育活动的人被归类为久坐不动者，其他受试者被归类为偶尔锻炼者。1977年至1994年同性双胞胎全因死亡率和不一致死亡率。在整个队列中，1253名受试者死亡，与久坐者相比，偶尔锻炼者的死亡风险比为0.71（95%CI，0.62-0.81），条件锻炼者为0.57（95%CI，0.45-0.74）（P趋势
Context.-Physical activity and fitness are believed to reduce premature mortality, but whether genetic factors modify this effect is not known.Objective.-To investigate leisure physical activity and mortality with respect to familial aggregation of health habits during childhood and factors that may enable some individuals to achieve higher levels of fitness.Design.-Prospective twin cohort study.Setting.-Finland.Subjects.-In 1975, at baseline, 7925 healthy men and 7977 healthy women of the Finnish Twin Cohort aged 25 to 64 years who responded to a questionnaire on physical activity habits and known predictors of mortality. Those who reported exercising at least 6 times per month with an intensity corresponding to at least vigorous walking for a mean duration of 30 minutes were classified as conditioning exercisers, those who reported no leisure physical activity were classified as sedentary, and other subjects were classified as occasional exercisers.Main Outcome Measures.-All-cause mortality and discordant deaths among same-sex twin pairs from 1977 through 1994.Results.-Among the entire cohort, 1253 subjects died, The hazard ratio for death adjusted for age and sex was 0.71 (95% confidence interval [CI], 0.62-0.81) in occasional exercisers and 0.57 (95% CI, 0.45-0.74) in conditioning exercisers, compared with those who were sedentary (P for trend