Course of the optic nerve fibers through the lamina cibrosa in human eyes
Course of the optic nerve fibers through the lamina cibrosa in human eyes
复制标题
DOI：
10.1007/bf00448803
复制
发表时间：
1996-09-01
影响因子：
2.7
通讯作者：
Naumann, GOH
中科院分区：
文献类型：
--
作者：
Dichtl, A;Jonas, JB;Naumann, GOH
背景：本研究探讨视神经纤维穿过筛板的区域差异是否可能是青光眼视神经纤维丢失的局部易感性因视盘不同区域不同而不同的原因之一。方法：本研究包括34只因周围脉络膜恶性黑色素瘤而摘除眼球的人眼，无前房角或视神经受累。对通过瞳孔和视盘的前后部切片进行组织形态计量学评估。结果：在视盘中央区和周围区，筛板厚度和神经纤维通过的筛板“通道”长度均显著大于中央区(P
Background: This study investigated whether regional variations in the course of the optic nerve fibers through the lamina cribrosa may be one of the reasons why the local susceptibility for glaucomatous optic nerve fiber loss differs among the various regions of the optic disc.Methods: The study included 34 human eyes enucleated because of a malignant melanoma of the peripheral choroid without involvement of the anterior chamber angle or the optic nerve. Anterior-posterior sections through the pupil and the optic disc were histomorphometrically evaluated. In the central region and the peripheral part of the optic disc, we measured the thickness of the lamina cribrosa and the length of the lamina cribrosa ''channels'' through which the nerve fibers pass.Results: In the peripheral parts of the disc, compared with its central region, the lamina cribrosa was significantly thicker (P