Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds [New Synthetic Methods (69)]
Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds [New Synthetic Methods (69)]
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生产生物和化学有用化合物的微生物和酶法[新合成方法 (69)]
DOI：
10.1002/anie.198806221
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发表时间：
1988
影响因子：
--
通讯作者：
S. Shimizu
中科院分区：
文献类型：
--
作者：
H. Yamada;S. Shimizu
近年来，合成有机化学领域最显着的发展是生物系统在化学反应中的应用。酶和酶系统催化的反应比更传统的有机反应表现出更大的特异性。生物和/或酶促合成和转化，即“微生物转化”，具有巨大的潜力。其中一些反应已被证明在合成有机化学和生物技术领域具有有用的应用。本文回顾了快速发展的微生物转化领域的现状、特别是与传统有机合成方法相关的方法、可用的技术程序和应用领域。
In recent years, the most significant development in the field of synthetic organic chemistry has been the application of biological systems to chemical reactions. Reactions catalyzed by enzymes and enzyme systems display far greater specificities than more conventional organic reactions. Biological and/or enzymatic syntheses and transformations, that is, “microbial transformations,” have great potential. Some of these reactions have already been shown to have useful applications in the fields of synthetic organic chemistry and biotechnology. This article reviews the current status of the rapidly developing field of microbial transformation, the methodology, available technological procedures, and fields of application being described especially in relation to conventional organic synthesis methods.