Circadian sleep-wake cycle organization in squirrel monkeys.
Circadian sleep-wake cycle organization in squirrel monkeys.
复制标题
松鼠猴的昼夜节律睡眠-觉醒周期组织。
DOI：
10.1152/ajpregu.1985.248.3.r353
复制
发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Moore-Ede,MC
中科院分区：
文献类型：
--
作者：
Wexler,DB;Moore-Ede,MC
为了探讨体温昼夜节律与睡眠-觉醒阶段之间的关系，对4只松鼠猴进行了无限制的体温、自发活动、脑电图、电图和肌电图监测。连续记录每只动物的几个12小时的光暗（LD）周期，然后在恒定照明（LL）几天后。所有动物保持巩固的睡眠-觉醒周期，并有一个较长的昼夜节律周期（平均24.7小时）在LL比LD（平均24.1小时）。增加的时间反映了更大的时间，每个昼夜周期花费清醒的LL（平均14.0小时）比LD（平均12.8小时）。LL组的夜间NREM睡眠总量（平均6.5 h）少于LD组（平均8.2 h）。LL（187 +/- 6度）比LD（170 +/- 2度）晚出现睡眠发作。由于LD和LL条件下NREM睡眠的昼夜节律相位测量值不变，因此睡眠开始的差异反映了NREM昼夜节律波形的平衡变化。两种情况下的唤醒阶段相同（平均342度）。总之，在自由运行的松鼠猴保持稳定的巩固昼夜睡眠-觉醒周期大于24小时，但他们表现出最小的内部相位重构。
To investigate the relationship between circadian rhythms of body temperature and sleep-wake stages, four squirrel monkeys were prepared for unrestrained monitoring of temperature, locomotor activity, electroencephalogram, electroculogram, and electromyogram. Continuous records for each animal were made for several 12-h light-dark (LD) cycles and then after a few days in constant illumination (LL). All animals maintained consolidated sleep-wake cycles and had a longer circadian period (mean 24.7 h) in LL than in LD (mean 24.1 h). The increased period reflected greater time per circadian cycle spent awake in LL (mean 14.0 h) than in LD (mean 12.8 h). Total night NREM sleep was less in LL (mean 6.5 h) than in LD (mean 8.2 h). Sleep onset occurred at later phases in LL (187 +/- 6 degrees) than in LD (170 +/- 2 degrees). Because the circadian phase measure of NREM sleep was unchanged between LD and LL conditions, the difference in sleep onsets reflected balanced changes in NREM circadian waveforms. Wake-up phases were the same in both conditions (mean 342 degrees). In summary, during free run squirrel monkeys maintain a stable consolidated circadian sleep-wake cycle with a period greater than 24 h, but they exhibit only minimal internal phase restructuring.