Ultrananocrystalline Diamond Integration with Pyrolytic Carbon Components of Mechanical Heart Valves.
Ultrananocrystalline Diamond Integration with Pyrolytic Carbon Components of Mechanical Heart Valves.
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DOI：
10.1016/j.diamond.2015.11.020
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发表时间：
2016-01-01
影响因子：
4.1
通讯作者：
Carlisle J
中科院分区：
文献类型：
--
作者：
Zeng H;Yin W;Catausan G;Moldovan N;Carlisle J
在本报告中，已经证明了将超纳米晶金刚石（UNCD）与热解碳（PyC）基机械心脏瓣膜集成的想法。该报告讨论了在金刚石涂层过程中避免石墨化和膜层分层的策略。拉曼和划痕测试表明，高纯度的UNCD膜可以牢固地附着在PyC衬底上。凝血酶生成研究表明UNCD对新鲜人血小板具有极好的生物相容性。这些结果表明，UNCD可能是下一代心脏瓣膜和其他植入装置的表面材料的良好候选者。
In this report, an idea of integrating ultrananocrystalline diamond (UNCD) with pyrolytic carbon (PyC) –based mechanical heart valves, has been demonstrated. The report addresses the strategies to avoid graphitization and film delamination during the diamond coating. Raman and scratch tests showed that a UNCD film with high purity could adhere to the PyC substrate strongly. A thrombin generation study demonstrated an excellent biocompatibility of UNCD towards fresh human platelets. These results suggest that UNCD could be a good candidate of surface material for next generation heart valves and other implantable devices.