Influence of anisotropy on the mechanical behaviour of bioprosthetic heart valves
Influence of anisotropy on the mechanical behaviour of bioprosthetic heart valves
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DOI：
10.1080/030919099294050
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发表时间：
1999-11-01
影响因子：
--
通讯作者：
Patterson, EA
中科院分区：
文献类型：
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作者：
Burriesci, G;Howard, IC;Patterson, EA
化学改性的心包通常用于制造人工生物心脏瓣膜。该材料表现出非线性弹性行为，并且与大多数其他生物软组织一样，其延展性是正交各向异性的。本文用有限元法研究了心包的自然正交各向异性对心包心脏瓣膜在整个心动周期内力学行为的影响。已经创建了二尖瓣瓣叶的模型，将组织的材料定义为正交各向异性非线性弹性。已经分析了组织的两个优先正交方向（轴向和周向）。结果表明，即使使用少量的正交各向异性（正交各向异性指数为1.5）也会显著影响瓣膜的机械性能，并且纤维的适当取向有助于优化瓣叶中的应力分布。
Chemically modified pericardium is commonly used in the fabrication of bioprosthetic heart valves. This material exhibits non-linear elastic behaviour and as for most other biological soft tissues, if is orthotropic in its extensibility. The influence of the natural orthotropy of pericardium on the mechanical behaviour of pericardial heart values during the whole cardiac cycle has been studied, using the finite element method. A model of the leaflet of a bicuspid valve has been created, defining the material of the tissue as orthotropic non-linear elastic. Two preferential orthogonal orientations of the tissue have been analysed (axial and circumferential). The results show that even a small amount of orthotropy tan orthotropy index of 1.5 has been used) can significantly affect the mechanical behaviour of the valve, and that an appropriate orientation of the fibres can contribute to optimizing the stress distribution in the leaflets.