ON ORIENTATION OF CENTRIOLES IN DIVIDING CELLS, AND ITS SIGNIFICANCE - A NEW CONTRIBUTION TO SPINDLE MECHANICS
ON ORIENTATION OF CENTRIOLES IN DIVIDING CELLS, AND ITS SIGNIFICANCE - A NEW CONTRIBUTION TO SPINDLE MECHANICS
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DOI：
10.2307/1539532
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发表时间：
1961-01-01
影响因子：
1.6
通讯作者：
COSTELLO, DP
中科院分区：
文献类型：
--
作者：
COSTELLO, DP
无体腔虫卵休眠第一卵裂中期的中心粒。是稍微弯曲的杆（长度为5 μ或更长），彼此成直角并与主轴轴线成直角。直角取向和预测的行为，与早期的观察中心粒的方向和行为的蟋蟀和半翅目的精母细胞，导致一个新的假说，这可能会解释，部分卵裂模式：（a）的方向的中心粒和它们的生殖方式决定的路径的子中心粒的分离。(b)这反过来又决定了下一次分裂时纺锤体主轴的方向，从而决定了子细胞彼此之间的相对位置。(c)子细胞的这种排列由初级细胞的结缔组织（纺锤体残余物加上皮层）维持一段时间。
The centrioles of the resting first cleavage metaphase of the egg of the acoel, Polychoerus carmelensis. are slightly curved rods(5u or more in length) oriented at right angles to each other and to the spindle axis. The right angle orientation and predicted behavior, compared with earlier observations by others on centriole orientation and behavior in the spermatocytes of Gryllidae and Hemiptera, lead to a new hypothesis, which may account, in part, for cleavage patterns: (a) The orientation of the centrioles and their mode of reproduction determines the path of separation of daughter centrioles. (b) This, in turn, determines the orientation of the main axis of the spindle for the next division, and hence, the relative position of daughter cells with respect to each other. (c) This arrangement of daughter cells is maintained, for a time, by the primary cell connective( spindle remnant plus cortical layer) .