Lanthanide Complexes of Polyacid Ligands derived from 2, 6‐bis(pyrazol‐1‐yl)pyridine, pyrazine, and 6, 6′‐bis(pyrazol‐1‐yl)‐2, 2′‐bipyridine: Synthesis and luminescence properties
Lanthanide Complexes of Polyacid Ligands derived from 2, 6‐bis(pyrazol‐1‐yl)pyridine, pyrazine, and 6, 6′‐bis(pyrazol‐1‐yl)‐2, 2′‐bipyridine: Synthesis and luminescence properties
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2, 6-双(吡唑-1-基)吡啶、吡嗪和6, 6-双(吡唑-1-基)-2, 2-联吡啶衍生的稀土配合物：合成和发光性质
DOI：
10.1002/hlca.19970800108
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发表时间：
1997
影响因子：
1.8
通讯作者：
E. Brunet
中科院分区：
文献类型：
--
作者：
J. Rodríguez;R. Sedano;Gemma Barroso;O. Juanes;E. Brunet
合成了N，N，N‘，N’-{2，6-bis[3-(aminomethyl)pyrazol-1-yl]-4-methoxypyridine}tetrakis(acetic酸)(1)，N，N，N‘，N’-{2，6-bis[3-(aminomethyl)pyrazol-1-yl]pyrazine}-tetrakis(acetic酸)(2)和N，N，N‘，N’-{6，6‘-双[3-(氨甲基)吡唑-1-基]-2，2‘-联吡啶}四(乙酸)(3)。配体1-3在水中与EuIII、TbIII、SmIII和DyIII形成稳定的络合物，测量了它们的相对发光产额、三态能量和发射衰减寿命。测定了稀土离子第一配位球内H2O分子的数目。1-3与母体三杂环N，N，N‘，N’-{2，6-bis[3-(aminomethyl)pyrazol-l-yl]pyridine}tetrakis(acetic酸]的EuⅢ和TbⅢ配合物的数据比较表明，吡啶环被修饰为吡嗪或2，2‘-联吡啶强烈地改变了配合物的发光性质。在1的C(4)处的MEO取代保持了母体化合物所描述的优良性质，并提供了附加的官能团，该官能团将用于在生物亲和力应用中将标记附着到生物分子上。
The synthesis of three novel pyrazole-containing complexing acids, N,N,N′,N′-{2, 6-bis[3-(aminomethyl)pyrazol-1-yl]-4-methoxypyridine}tetrakis(acetic acid)(1), N,N,N′,N′-{2, 6-bis[3-(aminomethyl)pyrazol-1-yl]pyrazine}-tetrakis(acetic acid) (2), and N,N,N′,N′-{6, 6′-bis[3-(aminomethyl)pyrazol-1-yl]-2, 2′-bipyridine}tetrakis(acetic acid) (3) is described. Ligands 1–3 formed stable complexes with EuIII, TbIII, SmIII, and DyIII in H2O whose relative luminescence yields, triplet-state energies, and emission decay lifetimes were measured. The number of H2O molecules in the first coordination sphere of the lanthanide ion were also determined. Comparison of data from the EuIII and TbIII complexes of 1–3 and those of the parent trisheterocycle N,N,N′,N′-{2, 6-bis[3-(aminomethyl)pyrazol-l-yl]pyridine}tetrakis(acetic acid) showed that the modification of the pyridine ring for pyrazine or 2, 2′-bipyridine strongly modify the luminescence properties of the complexes. MeO Substitution at C(4) of 1 maintain the excellent properties described for the parent compound and give an additional functional group that will serve for attaching the label to biomolecules in bioaffinity applications.
使用 Eu3 发光光谱表征卫星烟草坏死病毒的五重 Ca2 结合位点：稀土离子之间具有显着的尺寸选择性。
影响因子：
3.8
作者：
Burroughs,SE;Eisenman,G;HorrocksJr,WD
通讯作者：
HorrocksJr,WD