Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues

Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues
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荧光 2D 肽片揭示了 CD47 作为肝细胞癌和胆管癌组织分析的潜在生物标志物。

DOI:
10.1002/adma.201604253
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发表时间:
2017-02-02
期刊:
影响因子:
29.4
通讯作者:
Wang, Hong-Yang
Wang, Hong-Yang
中科院分区:
材料科学1区
文献类型:
--
作者:
Ma, Yun-Han;Dou, Wei-Tao;Wang, Hong-Yang

文献摘要

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二维肽片揭示了CD47作为一种潜在的生物标记物来成像肝癌和胆管癌细胞和组织。水溶性二维MoS2与多肽探针的超分子组装产生了适合于在临床标本上的健康组织上分析肝癌和胆管癌组织的二维多肽片。
A 2D peptidosheet unravels CD47 as a potential biomarker to image hepatocarcinoma and cholangiocarcinoma cells and tissues. Supramolecular assembly between water-soluble 2D MoS2 and a peptide probe produces the 2D peptidosheet suited for the profiling of hepatocarcinoma and cholangiocarcinoma tissues over healthy tissues on clinical specimens.