Fundamentals of clinical outcomes assessment for spinal disorders: study designs, methodologies, and analyses.
Fundamentals of clinical outcomes assessment for spinal disorders: study designs, methodologies, and analyses.
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DOI：
10.1055/s-0035-1547525
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发表时间：
2015-04
影响因子：
2.4
通讯作者：
Samartzis D
中科院分区：
文献类型：
--
作者：
Vavken P;Ganal-Antonio AK;Shen FH;Chapman JR;Samartzis D
研究设计 广泛的叙事性回顾。目的随着新技术的不断发展，脊柱疾病的 治疗也在不断发展。无论如何，对患者结果的评估是了解各种治疗干预措施的安全性和有效性的关键。因此，循证脊柱护理是脊柱专家医疗机构的重要组成部分，以努力批判性地分析已报道的文献并进行研究，以努力改善患者护理并改变临床实践。下面的文章是由两部分组成的系列文章的第一部分，旨在引起人们对各种研究设计的利弊、方法问题以及统计学考虑的关注。方法 对同行评议的文献进行广泛的回顾，不考虑发表的语言，涉及研究设计及其方法和统计学概念。结果 已报道了大量涉及研究设计及其方法学考虑的文章和概念，以及统计分析概念。它们在脊柱相关疾病和疾病方面的应用也被注意到。结论 了解研究设计的基本原则及其方法学考虑和统计分析，可以进一步推动和改进未来与脊柱相关的研究。
Study Design A broad narrative review. Objective Management of spinal disorders is continuously evolving, with new technologies being constantly developed. Regardless, assessment of patient outcomes is key in understanding the safety and efficacy of various therapeutic interventions. As such, evidence-based spine care is an essential component to the armamentarium of the spine specialist in an effort to critically analyze the reported literature and execute studies in an effort to improve patient care and change clinical practice. The following article, part one of a two-part series, is meant to bring attention to the pros and cons of various study designs, their methodological issues, as well as statistical considerations. Methods An extensive review of the peer-reviewed literature was performed, irrespective of language of publication, addressing study designs and their methodologies as well as statistical concepts. Results Numerous articles and concepts addressing study designs and their methodological considerations as well as statistical analytical concepts have been reported. Their applications in the context of spine-related conditions and disorders were noted. Conclusion Understanding the fundamental principles of study designs and their methodological considerations as well as statistical analyses can further advance and improve future spine-related research.