Indocyanine green selectively stains the internal limiting membrane
Indocyanine green selectively stains the internal limiting membrane
复制标题
DOI：
10.1016/s0002-9394(00)00924-7
复制
发表时间：
2001-03-01
影响因子：
4.2
通讯作者：
Kampik, A
中科院分区：
文献类型：
--
作者：
Gandorfer, A;Messmer, EM;Kampik, A
目得：为了证明吲哚菁绿色是否染色视网膜的内界膜或残留的玻璃体cortic.METHODS：我们报告了10例连续患者的10只眼睛的玻璃体黄斑界面的术中染色模式，这些患者因黄斑裂孔形成和弥漫性糖尿病黄斑水肿而接受了吲哚菁绿色染色的玻璃体切除术。在5例黄斑裂孔患者的5只眼睛中，玻璃体后脱离后黄斑的吲哚菁绿色染色导致了先前未观察到的可辨别膜的立即可见性。在5例弥漫性糖尿病黄斑水肿和玻璃体皮质粘连患者的5只眼中，吲哚菁绿色未能染色玻璃体黄斑界面。剥除残留玻璃体皮质后，再次用吲哚菁绿色染料染色，可见明显的内界膜，光镜和透射电镜均显示内界膜为所有标本中已被染色和去除的膜。结论：吲哚菁绿色选择性地染色内界膜。使用吲哚菁绿色作为活体染料对玻璃体黄斑界面进行染色使外科医生能够区分残留的玻璃体皮质和内界膜，并且它允许更安全和更容易地去除内界膜。(Am J Ophthalmol 2001;131：387-388. (C)2001年，Elsevier Science Inc.版权所有© 2016
PURPOSE: To demonstrate whether indocyanine green stains the inner limiting membrane of the retina or residual vitreous cortex.METHODS: We report on the intraoperative staining patterns of the vitreomacular interface in 10 eyes of 10 consecutive patients who underwent vitrectomy with indocyanine green staining for macular hole formation and diffuse diabetic macular edema.RESULTS: In five eyes of five patients with macular holes, indocyanine green staining of the macula after posterior vitreous detachment resulted in an immediate visibility of a discernable membrane that was not previously seen. In five eyes of five patients with diffuse diabetic macular edema and adherent cortical vitreous, indocyanine green failed to stain the vitreomacular interface. After peeling off the residual vitreous cortex, however, a discernable membrane could be identified using indocyanine green dye again, Light and transmission electron microscopy revealed the inner limiting membrane as the membrane that had been stained and removed in all specimens.CONCLUSION: Indocyanine green selectively stains the inner limiting membrane. Staining of the vitreomacular interface using indocyanine green as a vital dye enables the surgeon to distinguish between the residual vitreous cortex and the inner limiting membrane, and it allows safer and easier removal of the inner limiting membrane. (Am J Ophthalmol 2001;131:387-388. (C) 2001 by Elsevier Science Inc. All rights reserved.).