Impeded lung function in moulders and coremakers handling furan resin sand

Impeded lung function in moulders and coremakers handling furan resin sand
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处理呋喃树脂砂的造型工和制芯工的肺功能受损

DOI:
10.1007/bf00381565
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发表时间:
1991
影响因子:
3
通讯作者:
U. Ulfvarson
U. Ulfvarson
中科院分区:
医学3区
文献类型:
--
作者:
Mats Åkhman;R. Alexandersson;U. Ekholm;B. Bergstrom;Monica Dahlgvist;U. Ulfvarson

文献摘要

被引文献

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本文对39名呋喃树脂砂作业工人和27名非呋喃树脂砂作业工人进行了轮班前后的肺功能检查。对呋喃树脂砂暴露组和对照组的28名受试者进行动态肺功能测定和氮洗评价。其余11名受试者暴露于呋喃树脂砂进行了研究,使用静态和动态肺量计和CO单次呼吸技术。对糠醇的时间加权平均接触量约为7毫克/立方米,峰值超过瑞典目前的短期接触限值(40毫克/立方米)。在所有组中,在轮班期间按时间加权的呼吸性粉尘和甲醛暴露量分别为< 2 mg/m3和0.4 mg/m3。在轮班期间,28名暴露受试者比对照组有更多的气道症状,表现出用力肺活量平均下降0.21,但其他肺功能变量没有下降。其余11例暴露受试者表现出转移后总肺容量下降。结果表明,急性限制性暴露于呋喃树脂砂诱导,但其内在机制尚不清楚。未观察到慢性肺功能损害。
SummaryA total of 39 moulders and coremakers exposed to furan resin sand and 27 unexposed local controls were examined by lung-function tests before and after a work shift. In all, 28 of the subjects exposed to furan resin sand and the control group were evaluated by dynamic spirometry and nitrogen washout. The remaining 11 subjects exposed to furan resin sand were studied using both static and dynamic spirometry and the CO single-breath technique. The time-weighted average exposure to furfuryl alcohol was about 7 mg/m3, with peak values exceeding the present Swedish short-term exposure limit (40 mg/m3). The exposure to respirable dust and formaldehyde as time-weighted over the shift was < 2 mg/m3 and 0.4 mg/m3, respectively, in all groups. During the work shift studied, the 28 exposed subjects had more complaints of airway symptoms than did the controls, showing an average decrease of 0.21 in forced vital capacity but no fall in any other lung-function variable. The remaining 11 exposed subjects demonstrated a post-shift decrease in total lung capacity. The results indicate an acute restrictiveness induced by exposure to furan resin sand, but the underlying mechanism is unclear. Chronic impairment of lung function was not observed.