Improving accuracy in DOSY and diffusion measurements using triaxial field gradients
Improving accuracy in DOSY and diffusion measurements using triaxial field gradients
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DOI：
10.1016/j.jmr.2016.06.011
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发表时间：
2016-09-01
影响因子：
2.2
通讯作者：
Morris, Gareth A.
中科院分区：
文献类型：
--
作者：
Kiraly, Peter;Swan, Iain;Morris, Gareth A.
溶液中扩散的NMR测量，无论主要是定量的，还是定性的（如在DOSY中，扩散有序光谱），都可能特别苛刻。在这里，我们展示了如何使用适当的横向（x，y）脉冲场梯度，正交于更常见的z轴脉冲场梯度施加沿着样品的长轴，可以大大减少扩散实验中的系统误差的两个重要来源。这些是由样品对流引起的额外信号衰减，以及由磁场和场梯度脉冲产生的场频率锁定干扰引起的梯度相关信号相移。(C)2016年6月，作者。爱思唯尔公司出版
NMR measurements of diffusion in solution, whether primarily quantitative, or, (as in DOSY, Diffusion Ordered Spectroscopy) qualitative, can be particularly demanding. Here we show how the use of appropriate transverse (x, y) pulsed field gradients, orthogonal to the more usual z axis pulsed field gradient applied along the long axis of the sample, can greatly reduce two important sources of systematic error in diffusion experiments. These are the extra signal attenuation caused by sample convection, and gradient-dependent signal phase shifts caused by the magnetic field and field-frequency lock disturbances generated by field gradient pulses. (C) 2016 The Authors. Published by Elsevier Inc.