Synthesis of fused imidazo azepine derivatives by sequential van Leusen/enyne metathesis reactions

Synthesis of fused imidazo azepine derivatives by sequential van Leusen/enyne metathesis reactions
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DOI:
10.1016/j.tetlet.2005.10.089
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发表时间:
2005-12-26
影响因子:
1.8
通讯作者:
Djuric, SW
Djuric, SW
中科院分区:
化学4区
文献类型:
--
作者:
Gracias, V;Gasiecki, AF;Djuric, SW

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A facile synthesis of fused imidazo azepine derivatives by a van Leusen/intramolecular enyne metathesis synthetic sequence is reported. The two-step reaction sequence generates compounds of significant molecular complexity from simple starting materials in an expedient fashion with good overall yields. (c) 2005 Elsevier Ltd. All rights reserved.