Proton MR spectroscopy of gliomatosis cerebri: case report of elevated myoinositol with normal choline levels.
Proton MR spectroscopy of gliomatosis cerebri: case report of elevated myoinositol with normal choline levels.
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脑胶质瘤病的质子磁共振波谱：肌醇升高但胆碱水平正常的病例报告。
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
C. Petito
中科院分区：
文献类型：
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作者：
E. Saraf‐Lavi;B. Bowen;P. Pattany;E. Sklar;J. Murdoch;C. Petito
A 69-year-old woman presented with clinical and imaging findings suspicious for gliomatosis cerebri, later confirmed by biopsy (moderately cellular, infiltrating glioma). Single voxel proton MR spectroscopy (TE 20 and TE 135) and spectroscopic imaging (TE 135) performed at admission showed normal choline, decreased N-acetyl, and elevated myo-inositol levels relative to creatine. The primary conclusion is that in suspected cases of gliomatosis cerebri, myo-inositol/creatine and myo-inositol/N-acetyl should be determined because they may provide evidence of tumor, even though choline/creatine is normal. A corollary to this conclusion is that choline/creatine may be misleading if used to demarcate infiltrating glioma from edema.
