Salivary mutans streptococci and lactobacilli levels after ingestion of the probiotic bacterium Lactobacillus reuteri ATCC 55730 by straws or tablets
Salivary mutans streptococci and lactobacilli levels after ingestion of the probiotic bacterium Lactobacillus reuteri ATCC 55730 by straws or tablets
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DOI：
10.1080/00016350600801709
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发表时间：
2006-10-01
影响因子：
2
通讯作者：
Twetman, Svante
中科院分区：
文献类型：
--
作者：
Caglar, Esber;Cildir, Sule Kavaloglu;Twetman, Svante
Objective.先前的研究表明，乳制品中的乳酸杆菌衍生的益生菌可能会影响口腔生态，但不同摄入媒介物的影响很少受到关注。本研究的目的是调查益生菌罗伊氏乳杆菌ATCC 55730的唾液变形链球菌和乳酸杆菌在年轻人的水平上的效果时，摄入两种不同的交付系统。材料与方法。该材料包括120名健康的年轻人（21 - 24岁），采用安慰剂对照平行组研究设计。受试者被随机分为四组：A组通过事先准备好的含L. reuteri ATCC 55730，每日一次，持续3周，而B组在同一时期通过安慰剂吸管饮用200 ml水。C组给予含L. reuteri ATCC 55730，每日一次，持续3周，而D组接受不含细菌的安慰剂片剂。在基线和最后一次摄入后1天，使用椅旁试剂盒对唾液变形链球菌和乳酸杆菌进行计数。结果在通过吸管（p < 0.05）和片剂（p < 0.01）摄入益生菌后，记录到变形链球菌水平的统计学显著降低，这与安慰剂对照相反。乳酸杆菌也有类似但不显著的趋势。结论.短期每日摄入由准备好的吸管或锭剂递送的乳酸杆菌衍生的益生菌降低了年轻人唾液中变形链球菌的水平。
Objective. Previous studies have suggested that lactobacilli-derived probiotics in dairy products may affect oral ecology, but the impact of different vehicles of ingestion has received little attention. The aim of the present study was to investigate the effect of the probiotic bacterium Lactobacillus reuteri ATCC 55730 on the levels of salivary mutans streptococci and lactobacilli in young adults when ingested by two different delivery systems. Material and Methods. The material comprised 120 healthy young adults ( 21 - 24 years) and a placebo-controlled study design with parallel arms was utilized. The subjects were randomly assigned to four equally sized groups: group A drank 200 ml of water through a prepared straw containing L. reuteri ATCC 55730 once daily for 3 weeks, while group B took 200 ml water through a placebo straw during the same period. Group C was given one tablet containing L. reuteri ATCC 55730 once daily for 3 weeks, while group D received placebo tablets without bacteria. Salivary mutans streptococci and lactobacilli were enumerated with chair-side kits at baseline and 1 day after the final ingestion. Results. A statistically significant reduction of the mutans streptococci levels was recorded after ingestion of the probiotic bacteria via the straw ( p < 0.05) and the tablets ( p < 0.01), which was in contrast to the placebo controls. A similar but non-significant trend was seen for lactobacilli. Conclusions. A short-term daily ingestion of lactobacilli-derived probiotics delivered by prepared straws or lozenges reduced the levels of salivary mutans streptococci in young adults.