Demographic and clinical factors associated with recovery of poststroke dysphagia: A meta-analysis.

Demographic and clinical factors associated with recovery of poststroke dysphagia: A meta-analysis.
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DOI:
10.1002/brb3.3033
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发表时间:
2023-06
期刊:
影响因子:
3.1
通讯作者:
Dou, Zulin
Dou, Zulin
中科院分区:
心理学4区
文献类型:
--
作者:
Wang, Lian;Qiao, Jia;Sun, Fang;Wei, Xiaomei;Dou, Zulin

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中风后吞咽困难 (PSD) 的恢复取决于多种因素。我们的目的是提供有关 PSD 恢复预测变量的证据。系统检索截至2022年9月21日的PubMed、Embase、Web of Science、CNKI、万方数据库、中文期刊维普数据库、中国生物医学文献服务系统(SinoMed)、Cochrane图书馆数据库,根据纳入标准对数据库中检索的文献进行筛选。使用纽卡斯尔-渥太华量表(NOS)评估纳入研究的方法学质量。进行荟萃分析以确定 PSD 的预后因素。 28 项研究合格,并且允许对 12 种潜在预后因素进行汇总分析。我们发现年龄较大、美国国立卫生研究院卒中量表(NIHSS)评分较高、日常生活活动能力(ADL)评分较低、体重指数(BMI)较低、入院时严重吞咽困难、误吸、脑干卒中、严重认知障碍和双侧半球卒中是PSD恢复的负面因素,而发病前早期干预和改良Rankin量表(mRS)=0是PSD恢复的保护因素。卒中类型与 PSD 预后之间没有显着相关性。本荟萃分析总结的 PSD 预后因素有助于制定合理的治疗方案,更好地促进卒中后吞咽功能的恢复。吞咽困难作为中风后常见的后遗症之一,给患者带来毁灭性的影响。有多种因素影响卒中后吞咽困难(PSD)的预后。研究表明,一些人口统计学和临床​​因素与 PSD 的预后相关,但缺乏对这些因素的总结。本荟萃分析通过汇总多项研究总结了相关因素与PSD预后之间的关联,这对于进一步确定个体化治疗以促进患者康复至关重要。
Poststroke dysphagia (PSD) recovery depends on various factors. We aimed to provide evidence concerning predictive variables for the recovery of PSD. PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP database of Chinese periodicals, Chinese biomedical literature service system (SinoMed), and Cochrane Library databases were systematically searched up to September 21, 2022. According to the inclusion criteria, the literature searched in the database was screened. The methodological quality of included studies was assessed using the Newcastle‐Ottawa Scale (NOS). Meta‐analysis was performed to identify the factors prognostic for PSD. Twenty‐eight studies were eligible, and pooled analyses were allowed for 12 potential prognostic factors. We identified older age, higher National Institutes of Health Stroke Scale (NIHSS) score, lower activities of daily living (ADL) score, lower body mass index (BMI), severe dysphagia on admission, aspiration, brainstem stroke, severe cognitive impairment, and bilateral hemispheric stroke were negative factors for the recovery of PSD, while early intervention and Modified Rankin Scale (mRS) = 0 before onset were protective factors for the recovery of PSD. There was no significant association between stroke type and prognosis of PSD. Prognostic factors of PSD summarized in this meta‐analysis could be useful for developing reasonable treatment plan to better promote recovery of swallowing function after stroke. Dysphagia, as one of the common sequelae after stroke, has a devastating impact on patients. There are several factors influencing the prognosis of post‐stroke dysphagia (PSD). Studies have been conducted to show that several demographic and clinical factors are associated with the prognosis of PSD, but a summary of these factors is lacking. This meta‐analysis summarizes the association between relevant factors and the prognosis of PSD by pooling multiple studies, which is crucial for further determining individualized treatment to promote patient recovery.
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