Curettage of giant congenital melanocytic nevi in neonates - A decade later
Curettage of giant congenital melanocytic nevi in neonates - A decade later
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DOI：
10.1001/archderm.138.7.943
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发表时间：
2002-07-01
影响因子：
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通讯作者：
Roseeuw, DL
中科院分区：
文献类型：
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作者：
De Raeve, LE;Roseeuw, DL
背景：目前，巨大先天性黑色素细胞痣（GCMN）的治疗方法还存在很大的不确定性。我们对GCMN患者的治疗方法基于两个主要考虑因素：（1）获得可接受的美容结果，以减少患者的心理社会不便，（2）尝试将恶性肿瘤的风险降至最低。在过去的10年里，我们一直在治疗GCMN的刮宫术在新生儿期。我们报告我们的经验和results.Observations：16个新生儿GCMN治疗刮宫1990年和2000年之间。获得活检标本，并对患者进行密切的临床随访。在大多数患者的美容和功能的结果是好的，而且，到目前为止，没有黑色素瘤已被观察到在这series.Conclusions：刮除术提供了一个足够的替代手术切除时，在第2周的生活。患者和父母对美容和功能结果感到满意，从而减少了由这些病变引起的心理社会不便。对这些儿童进行仔细的长期随访对监测最终的美容结果和减少恶性肿瘤的可能性至关重要。
Background: Currently, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. Our approach to patients with GCMN is based on 2 main considerations: (1) obtain an acceptable cosmetic result to decrease the psychosocial inconvenience to the patient, and (2) attempt to minimize the risk of malignancy. For the past 10 years we have treated GCMN by curettage in the neonatal period. We report our experience and results.Observations: Sixteen neonates with GCMN were treated by curettage between 1990 and 2000. Biopsy specimens were obtained and the patients received close clinical follow-up. In most patients cosmetic and functional results were good, and, to date, no melanoma has been observed in this series.Conclusions: Curettage offers an adequate alternative to surgical excision when performed during the first 2 weeks of life. Patients and parents are pleased with the cosmetic and functional results and thereby suffer less from the psychosocial inconvenience caused by these lesions. Careful long-term follow-up of these children is essential to monitor final cosmetic outcome and reduce the potential for malignancy.