Selective impairment in the retrieval of family relationships in person identification: A case study of delusional misidentification
Selective impairment in the retrieval of family relationships in person identification: A case study of delusional misidentification
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DOI：
10.1016/j.neuropsychologia.2007.06.003
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发表时间：
2007-01-01
期刊：
影响因子：
2.6
通讯作者：
Mori, Etsuro
中科院分区：
文献类型：
--
作者：
Abe, Nobuhito;Ishii, Hiroshi;Mori, Etsuro
我们描述了一个74岁的右利手的妇女谁表现出一种特殊形式的妄想性错误识别由于阿尔茨海默氏病（AD）合并特发性正常压力脑积水（iNPH）。这个病人最明显的症状是她经常把她的女儿误认为是她的姐妹篇。她的双侧内侧颞叶严重萎缩，额颞顶叶皮质以右半球为主灌注不足。详细的测试显示，她在检索自己与女儿/丈夫之间的家庭关系方面存在选择性缺陷（即，她将她的女儿误认为是她的姐妹篇并且将她的丈夫误认为是她的父亲），尽管能够检索她的家庭成员的名字和面孔，以及一些个人特定的语义信息（例如，职业，与他们有关。我们推测，这种特定类型的错误识别，可以引起未能更新语义记忆，通过编码新的情景记忆，由于右半球占主导地位的额颞功能障碍。(C)2007爱思唯尔有限公司保留所有权利。
We describe a 74-year-old, right-handed woman who exhibited a peculiar form of delusional misidentification due to Alzheimer's disease (AD) combined with idiopathic normal pressure hydrocephalus (iNPH). The patient's most distinctive symptom was that she often misidentified her daughters as her sisters. She had severe atrophy of the bilateral medial temporal lobe and right-hemisphere-dominant hypoperfusion in the fronto-temporo-parietal cortices. Detailed tests revealed that she had a selective deficit in retrieving the family relationships between herself and her daughters/husband (i.e., she misidentified her daughters as her sisters and her husband as her father), despite being able to retrieve the names and faces of her family members, and some person-specific semantic information (e.g., occupation) related to them. We speculate that this specific type of misidentification can be elicited by failure to update semantic memory through the encoding of new episodic memory due to right-hemisphere-dominant fronto-temporal dysfunction. (C) 2007 Elsevier Ltd. All rights reserved.