Psychosocial Burden and Glycemic Control During the First 6 Years of Diabetes: Results From the SEARCH for Diabetes in Youth Study
Psychosocial Burden and Glycemic Control During the First 6 Years of Diabetes: Results From the SEARCH for Diabetes in Youth Study
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DOI：
10.1016/j.jadohealth.2014.03.011
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发表时间：
2014-10-01
影响因子：
7.6
通讯作者：
Lawrence, Jean M.
中科院分区：
文献类型：
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作者：
Hood, Korey K.;Beavers, Daniel P.;Lawrence, Jean M.
目的：评估青少年糖尿病患者的心理社会负担，确定心理社会负担的轨迹，并检查心理社会负担和血糖控制之间的相互依赖关系，在前6年的糖尿病。S.在基线和基线后12、24和60个月进行的研究访问期间收集了20岁之前诊断为糖尿病的儿童。抽取血液，收集临床和人口统计学信息，并使用标准化抑郁症以及一般和糖尿病特定的健康相关生活质量（QOL）调查来评估心理社会负担。结果：在1，307名有基线数据的青少年（平均年龄，14.1 +/- 2.5岁）中，1，026人患有1型糖尿病，281人患有2型糖尿病。对于60个月随访的患者，糖化血红蛋白（A（1c））值较基线升高1.5%（1型，7.7%-9.3%，2型，7.3%-8.8%）。与1型糖尿病青少年相比，2型糖尿病青少年报告了更多的抑郁和较差的生活质量。对于每种糖尿病类型，A（1c）值升高的基线风险因素相似：糖尿病病程延长、少数民族状态和糖尿病生活质量下降（p
Purpose: To evaluate the psychosocial burden of adolescents with diabetes, determine the trajectory of psychosocial burden, and examine the interdependent relationships between psychosocial burden and glycemic control across the first 6 years of diabetes.Methods: Data from SEARCH for Diabetes in Youth, an observational study of U. S. children diagnosed with diabetes before the age of 20, were collected during study visits conducted at baseline and then at 12, 24, and 60 months after baseline. Blood was drawn, clinical and demographic information was collected, and psychosocial burden was evaluated using standardized depression and generic and diabetes-specific health-related quality of life (QOL) surveys.Results: Among the 1,307 adolescents (mean age, 14.1 +/- 2.5 years) with baseline data, 1,026 had type 1 diabetes and 281 had type 2 diabetes. For those with a 60-month follow-up visit, glycated hemoglobin (A(1c)) values rose 1.5% from baseline (type 1, 7.7%-9.3% and type 2, 7.3%-8.8%). Adolescents with type 2 diabetes reported more depression and poorer QOL than adolescents with type 1 diabetes. For each diabetes type, there were similar baseline risk factors for higher A(1c) values: longer diabetes duration, ethnic minority status, and declining diabetes QOL (p