Early Lymph Node Metastasis May Predict Poor Prognosis in Soft Tissue Sarcoma
Early Lymph Node Metastasis May Predict Poor Prognosis in Soft Tissue Sarcoma
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DOI：
10.1155/2019/6708474
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发表时间：
2019-12-12
影响因子：
1.5
通讯作者：
Yamashita, Toshihiko
中科院分区：
文献类型：
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作者：
Emori, Makoto;Tsuchie, Hiroyuki;Yamashita, Toshihiko
背景资料。在软组织肉瘤中，淋巴结转移(LNM)是一种相对罕见的事件。目前尚不清楚LNM检测的时间与患者预后之间的关系。病人和方法。我们回顾分析了2001-2015年间收治的33例LNM患者的临床病理特征。根据原发肿瘤诊断后8个月内出现LNM的患者对LNM诊断时间的分析进行分组。结果。原发肿瘤大小与淋巴结转移时间无明显相关性(Rs=0.0088，p=0.96)。16例患者的LNM检测持续时间为8个月。淋巴结转移持续时间为8个月的患者5年生存率分别为19%和71%(P=0.0016)。肺转移瘤19例。其中13例原发肿瘤诊断为LNM=8个月(P=0.01)。结论。早期LNM(
Background. Lymph node metastasis (LNM) is a relatively rare event in soft tissue sarcoma. An association between the timing of LNM detection and patient prognosis is presently unknown. Patients and Methods. We retrospectively analyzed the clinicopathological features of 33 patients with LNM between 2001 and 2015. Analysis of the timing of LNM diagnosis was grouped according to patients presenting LNM in either = 8 months after primary tumor diagnosis. Results. A relationship between the primary tumor size and the timing of the LNM was not significantly found (Rs = 0.0088, p=0.96). Sixteen patients had an LNM detection duration of = 8 months. The 5-year survival for patients with an LNM detection duration of = 8 months was 19% and 71%, respectively (p=0.0016). There were 19 patients with pulmonary metastases. Among them, there were 13 patients with a duration of primary tumor diagnosis to LNM of = 8 months (p=0.01). Conclusion. Early LNM (