Advances in Cardiac Organoids.
Advances in Cardiac Organoids.
复制标题
DOI：
10.31083/j.fbl2809221
复制
发表时间：
2023-09
期刊：
影响因子：
--
通讯作者：
Yu-Hong Wang;Ouyang Qing;Shuang Zhao;Yue Zhang;Run-Ze Tian;Yan-Ping Guo;Rui Zheng;Moussa Ide Nasser;Ge Li;Ping Zhu
中科院分区：
文献类型：
--
作者：
Yu-Hong Wang;Ouyang Qing;Shuang Zhao;Yue Zhang;Run-Ze Tian;Yan-Ping Guo;Rui Zheng;Moussa Ide Nasser;Ge Li;Ping Zhu
Cardiovascular diseases rank as the leading cause of death worldwide and are a major contributor to disability, posing a significant threat to human health. Organoids offer a partial simulation of the structure and function of the tissue of origin. It is a promising model that can supplement the disadvantages of two-dimensional culture and animal models. Due to the complexity of heart development, the research of cardiac organoids is still maturing. The advancement of technology has helped address certain challenges, but it has also unveiled new issues and complexities. This paper summarizes the application of organoids technology in the cardiovascular field, the common construction methods of cardiac organoids, and the latest progress of cardiac organoids in the fields of disease model construction, cardiac development research, drug research, and regenerative medicine. The future development and challenges of cardiac organoids are also addressed.
