Does Ramadan Fasting Alter Body Weight and Blood Lipids and Fasting Blood Glucose in a Healthy Population? A Meta-analysis
Does Ramadan Fasting Alter Body Weight and Blood Lipids and Fasting Blood Glucose in a Healthy Population? A Meta-analysis
复制标题
DOI：
10.1007/s10943-013-9687-0
复制
发表时间：
2014-06-01
影响因子：
2.8
通讯作者：
Karadag, Gulendam
中科院分区：
文献类型：
--
作者：
Kul, Seval;Savas, Esen;Karadag, Gulendam
在这项研究中，我们对自我对照队列研究进行了荟萃分析，比较了斋月前后的体重、血脂水平和空腹血糖水平，并考虑了性别差异。在2012年6月之前的几个数据库中检索了显示斋月禁食对健康受试者影响的研究，产生了30篇文章。这项荟萃分析的主要发现是，与斋月前的水平相比，斋月禁食后，两个性别组和整个组的低密度脂蛋白（SMD =-1.67，95% CI = -2.48至-0.86）和空腹血糖水平（SMD =-1.10，95% CI = -1.62至-0.58）均降低。此外，在雌性亚组中，体重（SMD =-0.04，95% CI =-0.20，0.12），总胆固醇（SMD = 0.05，95% CI = -0.51至0.60）和甘油三酯水平（SMD = 0.03，95% CI =-0.31，0.36）保持不变，而HDL水平（SMD = 0.86，95% CI = 0.11至1.61，p = 0.03）升高。在男性中，斋月禁食导致体重减轻（SMD =-0.24，95% CI =-0.36，-0.12，p = 0.001）。此外，在雄性动物中观察到总胆固醇（SMD =-0.44，95% CI = -0.77至-0.11）和LDL水平（SMD =-2.22，95% CI = -3.47至-0.96）显著降低，甘油三酯水平小幅降低（SMD =-0.35，95% CI = -0.67至-0.02）。总之，通过查看这些数据，很明显，与斋月前相比，斋月禁食可以有效地改变健康受试者的体重和一些生化参数，特别是男性。
In this study, we conducted a meta-analysis of self-controlled cohort studies comparing body weights, blood levels of lipids and fasting blood glucose levels before and after Ramadan taking into account gender differences. Several databases were searched up to June 2012 for studies showing an effect of Ramadan fasting in healthy subjects, yielding 30 articles. The primary finding of this meta-analysis was that after Ramadan fasting, low-density lipoprotein (SMD = -1.67, 95 % CI = -2.48 to -0.86) and fasting blood glucose levels (SMD = -1.10, 95 % CI = -1.62 to -0.58) were decreased in both sex groups and also in the entire group compared to levels prior to Ramadan. In addition, in the female subgroup, body weight (SMD = -0.04, 95 % CI = -0.20, 0.12), total cholesterol (SMD = 0.05, 95 % CI = -0.51 to 0.60), and triglyceride levels (SMD = 0.03, 95 % CI = -0.31, 0.36) remained unchanged, while HDL levels (SMD = 0.86, 95 % CI = 0.11 to 1.61, p = 0.03) were increased. In males, Ramadan fasting resulted in weight loss (SMD = -0.24, 95 % CI = -0.36, -0.12, p = 0.001). Also, a substantial reduction in total cholesterol (SMD = -0.44, 95 % CI = -0.77 to -0.11) and LDL levels (SMD = -2.22, 95 % CI = -3.47 to -0.96) and a small decrease in triglyceride levels (SMD = -0.35, 95 % CI = -0.67 to -0.02) were observed in males. In conclusion, by looking at this data, it is evident that Ramadan fasting can effectively change body weight and some biochemical parameters in healthy subjects especially in males compared to pre-Ramadan period.