Interaction between Bottlebrush Polymers and Phospholipid Membranes in Solutions.

Interaction between Bottlebrush Polymers and Phospholipid Membranes in Solutions.
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溶液中洗瓶刷聚合物与磷脂膜之间的相互作用

DOI:
10.3390/polym12123033
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发表时间:
2020-12-17
期刊:
影响因子:
5
通讯作者:
Li S
Li S
中科院分区:
工程技术3区
文献类型:
--
作者:
Dai X;Ji Y;Wang Z;He L;Wang X;Li S

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在这项工作中,瓶刷聚合物和磷脂膜之间的相互作用进行了研究,使用耗散粒子动力学模拟。通过计算体系参数,考察了聚合物与膜之间的弱吸附和强吸附现象。引入弹簧模型来解释瓶刷聚合物的形状因子和回转半径的变化,以及在拉伸过程中磷脂膜的序参量。本工作为瓶刷聚合物在生物过程中的应用提供了进一步的理解。
In this work, the interactions between bottlebrush polymers and phospholipid membranes were investigated using dissipative particle dynamics simulations. The weak and strong adsorption phenomena between the polymers and membranes were examined by calculating the system parameters. A spring model was introduced to explain the variances in the shape factors and the radius of gyration of the bottlebrush polymers, as well as the order parameters of the phospholipid membrane in the pulling processes. This work provides further understanding for the application of bottlebrush polymers in biological processes.
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期刊: MACROMOLECULES
影响因子: 5.5
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