The significance of blood cultures positive for emerging saprophytic moulds in cancer patients
The significance of blood cultures positive for emerging saprophytic moulds in cancer patients
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DOI：
10.1111/j.1469-0691.2004.00933.x
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发表时间：
2004-10-01
影响因子：
14.2
通讯作者：
Kontoyiannis, DP
中科院分区：
文献类型：
--
作者：
Lionakis, MS;Bodey, GP;Kontoyiannis, DP
在 30 名癌症患者中（1996-2002 年）评估了新出现的腐生霉菌（例如，Scedosporium apiospermum、Scedosporium prolificans、Paecilomyces spp.）的血培养呈阳性的意义。使用先前提出的评估曲霉菌血症的诊断标准。新出现的腐生霉菌的血培养呈阳性占所有阳性真菌培养的 1%。排除一例导管相关真菌血症。其余 29 例包括真实真菌血症 (n = 5)、可能真菌血症 (n = 1)、不确定真菌血症 (n = 7) 和污染真菌血症 (n = 16)。真正的真菌血症仅见于白血病患者和同种异体骨髓移植受者。 S. apiospermum 和 S. prorifans 是真正真菌血症的最常见原因。
The significance of blood cultures positive for emerging saprophytic moulds (e.g., Scedosporium apiospermum, Scedosporium prolificans, Paecilomyces spp.) was evaluated in 30 cancer patients (1996-2002). Diagnostic criteria proposed previously for evaluation of aspergillaemia were used. Blood cultures positive for emerging saprophytic moulds represented 1% of all positive fungal cultures. One case of catheter-related fungaemia was excluded. The remaining 29 cases consisted of true (n = 5), probable (n = 1), indeterminate (n = 7) fungaemia, and contamination (n = 16). True fungaemia was seen only in leukaemia patients and allogeneic bone marrow transplant recipients. S. apiospermum and S. prolificans were the commonest causes of true fungaemia.