TACTILE ACTIVITY IN PRIMATE PRIMARY SOMATOSENSORY CORTEX DURING ACTIVE ARM MOVEMENTS - CORRELATION WITH RECEPTIVE-FIELD PROPERTIES
TACTILE ACTIVITY IN PRIMATE PRIMARY SOMATOSENSORY CORTEX DURING ACTIVE ARM MOVEMENTS - CORRELATION WITH RECEPTIVE-FIELD PROPERTIES
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DOI：
10.1152/jn.1994.71.1.161
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发表时间：
1994-01-01
影响因子：
2.5
通讯作者：
KALASKA, JF
中科院分区：
文献类型：
--
作者：
COHEN, DAD;PRUDHOMME, MJL;KALASKA, JF
1. 在清醒、行为正常的猴子的初级体感皮层（SI）中分离出对侧手臂上595个具有触觉感受野（RFs）的单个神经元。2. 58%的触觉细胞在手臂向八个方向的主动运动或手臂在目标端点上的主动维持过程中表现出显著不同的活动水平。3. 许多活跃的触觉细胞的放电与运动方向呈单模态调谐，触觉群体的活动模式随手臂运动方向和姿势而有意义地变化。4. 手臂运动引起的活动强度通常低于直接触觉刺激细胞射频引起的强度。5. 任务相关活动的概率与某些射频特性相关，特别是细胞对皮肤横向拉伸的敏感性和避免射频在任何表面直接接触的被动手臂运动的敏感性。6. 这表明，与任务相关的活动主要是由于手臂在运动过程中改变几何形状时皮肤的机械变形激活了触觉感受器。7. 这些结果表明，在避免皮肤与外部表面直接接触的主动手臂运动中，SI产生了包含潜在本体感受信息的触觉活动。这种输入是否有助于运动引起的动觉感觉，本研究无法解决。
1. Five hundred ninety-five single neurons with tactile receptive fields (RFs) on the contralateral arm were isolated in the primary somatosensory cortex (SI) of awake, behaving monkeys. 2. Fifty-eight percent of the tactile cells showed significantly different levels of activity during active movements of the arm in eight directions or during active maintenance of the arm over the target endpoints. 3. The discharge of many of the active tactile cells was unimodally tuned with movement direction and the pattern of the tactile population activity varied in a meaningful fashion with arm movement direction and posture. 4. The intensity of the arm-movement-induced activity was typically less than that evoked by direct tactile stimulation of the cell's RF. 5. The probability of task-related activity was correlated with certain RF properties, in particular the sensitivity of the cell to lateral stretch of the skin and to passive arm movements that avoided direct contact of the RF on any surface. 6. This suggests that task-related activity results mainly from the activation of tactile receptors by mechanical deformation of the skin as the arm changes geometry during movement. 7. These results demonstrate that tactile activity containing potential proprioceptive information is generated in SI during active arm movements that avoid direct contact of the skin with external surfaces. Whether or not this input contributes to the kinesthetic sensations evoked by the movements cannot be resolved by this study.