Abnormal glucose tolerance in transfusion-dependent β-thalassemic patients

Abnormal glucose tolerance in transfusion-dependent β-thalassemic patients
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DOI:
10.2337/diacare.24.5.850
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发表时间:
2001-05-01
期刊:
影响因子:
16.2
通讯作者:
Fu, CC
Fu, CC
中科院分区:
医学1区
文献类型:
--
作者:
Chern, JPS;Lin, KH;Fu, CC

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目的-研究输血依赖性β-地中海贫血患者糖耐量异常的患病率和危险因素。研究设计和方法-共89例输血依赖性β-地中海贫血患者进行了采访。其中14人曾被诊断为糖尿病。在其余75名患者中,68名参与了口服葡萄糖耐量试验。采用独立t检验、卡方检验和Fisher精确检验确定潜在的危险因素。Logistic回归分析用于选择最能预测糖耐量异常的独立危险因素。双尾P值为
OBJECTIVE - To study the prevalence of and risk factors for abnormal glucose tolerance in transfusion-dependent beta -thalassemic patients.RESEARCH DESIGN AND METHODS - A total of 89 transfusion-dependent beta -thalassemic patients were interviewed. Diabetes was previously diagnosed in 14 of them. In the remaining 75 patients, 68 participated in an oral glucose tolerance test. Potential risk factors were identified using the independent t test, chi (2) test, and Fisher's exact test. Logistic regression analysis was used to select the independent risk factors that best predicted abnormal glucose tolerance. A two-tailed P value of