Minimally invasive stereotactic puncture and thrombolysis therapy improves long-term outcome after acute intracerebral hemorrhage.
Minimally invasive stereotactic puncture and thrombolysis therapy improves long-term outcome after acute intracerebral hemorrhage.
复制标题
微创立体定向穿刺溶栓治疗改善急性脑出血后的长期预后
DOI：
10.1007/s00415-011-5902-7
复制
发表时间：
2011-04
影响因子：
6
通讯作者：
Dong Q
中科院分区：
文献类型：
--
作者：
Zhou H;Zhang Y;Liu L;Huang Y;Tang Y;Su J;Hua W;Han X;Xue J;Dong Q
本研究的目的是评价微创立体定向穿刺术治疗急性脑出血的临床价值。采用随机对照临床试验。符合入选标准的急性脑出血患者122例，其中组(MISPTT组，MG)和常规开颅手术组(CC组，CG)各58例。比较两组患者的格拉斯哥昏迷评分(GCS)、术后并发症(PC)和再出血率。术后1年分别以格拉斯哥预后评分(GOS)、Barthel指数(BI)、改良≥评分(MRS)、病死率(CF)评定患者的血肿量(HV)、血肿体积(HV)、血肿体积(HV)和血肿体积(HV)。MG患者的GCS评分较对照组有明显改善。MG组PC的总发生率低于CG组。再出血率分别为9.4%和17.2%(P=0.243)。MG组和CG组CFS差异无统计学意义(分别为17.2%和25.9%，P=0.199)。代表HV<；50和HV≥50 mL远期疗效的GOS、BI和MRS在MG组明显优于CG组(P均<0.05)。这些数据表明，MISPTT不仅在创伤和安全性方面具有优势，而且MISPTT组的并发症较少，并有改善短期和长期结果的趋势。
The purpose of this study was to judge the clinical value of minimally invasive stereotactic puncture and thrombolysis therapy (MISPTT) for acute intracerebral hemorrhage (ICH). A randomized control clinical trial was undertaken. According to the enrollment criteria, 122 acute ICH cases were analyzed, of which 64 cases received MISPTT (MISPTT group, MG) and 58 cases received conventional craniotomy (CC group, CG). The Glasgow coma scale (GCS) scores, postoperative complications (PC), and rebleeding incidences were compared. Moreover, 1 year postoperation, the long-term outcomes of patients with regard to hematoma volume (HV) <50 mL and HV ≥50 mL were judged, respectively, by the Glasgow outcome scale (GOS), Barthel index (BI), modified Rankin Scale (mRS), and case fatality (CF). MG patients showed obvious amelioration in GCS score compared with that of CG patients. The total incidence of PC in MG decreased compared with that of CG. The incidences of rebleeding in MG and CG were 9.4 and 17.2%, respectively (P= 0.243). There were no obvious differences between the CFs of MG and CG (17.2 and 25.9%, respectively,P= 0.199). The GOS, BI, and mRS representing long-term outcome for both HV <50 mL and HV ≥50 mL in MG were ameliorated significantly greater than that in CG patients (allP< 0.05). These data suggest that there are advantages with MISPTT not only in trauma and safety, but the MISPTT group had fewer complications and a trend toward improved short-term and long-term outcomes.
登录
查看更多内容
影响因子：
8.3
作者：
Montes, JM;Wong, JH;Awad, IA
通讯作者：
Awad, IA
影响因子：
--
作者：
Marquardt, G;Wolff, R;Seifert, V
通讯作者：
Seifert, V
影响因子：
5.1
作者：
Peng, S. -Y.;Chuang, Y. -C.;Tseng, K. -H.
通讯作者：
Tseng, K. -H.
影响因子：
11
作者：
ANDERSON, CS;CHAKERA, TMH;JAMROZIK, KD
通讯作者：
JAMROZIK, KD
影响因子：
3.5
作者：
Barrett, RJ;Hussain, R;Carhuapoma, JR
通讯作者：
Carhuapoma, JR