RAPID RESISTANCE SHIFTS IN CAT CORTEX DURING CLICK-EVOKED RESPONSES
RAPID RESISTANCE SHIFTS IN CAT CORTEX DURING CLICK-EVOKED RESPONSES
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DOI：
10.1152/jn.1968.31.4.565
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发表时间：
1968-01-01
影响因子：
2.5
通讯作者：
GALAMBOS, R
中科院分区：
文献类型：
--
作者：
KLIVINGTON, KA;GALAMBOS, R
电阻和点击诱发电位同时记录通过同一电极急性放置在猫的听觉皮层。在诱发电位（EP）过程中，电极间电阻变化约1/105，先减小，后增大，最后在约100 ms内恢复到基线。诱发电阻变化（ERS）和EP在皮层表面有相似的分布，但EP达到其最大振幅在深度约1.0 mm的波形独立的深度。ERS的振幅受创伤、麻醉水平和温度变化的影响比EP更大。点击启动的神经冲动到达皮层激活一些过程，产生ERS除了启动这些事件产生EP。目前还没有数据来确定产生ERS的机制，但与神经元膜通透性变化相关的事件可能是原因。
Electrical resistance and click evoked potentials were recorded simultaneously through the same electrodes acutely placed in the auditory cortex of cats. During the course of the evoked potential (EP), the resistance between electrodes changed by about one part in 105, first decreasing, then increasing and finally returning to the baseline in about 100ms. The evoked resistance shifts (ERS) and the EP had similar distributions on the cortical surface, but the EP attained its maximum amplitude at a depth of about 1.0 mm with a waveshape independent of depth. The amplitude of the ERS was more strongly affected than that of the EP by trauma, anesthetic level and temperature changes. Click initiated neural impulses reaching the cortex activate some process yielding the ERS in addition to initiating those events yielding the EP. Data are not yet available to identify the mechanisms involved in generating the ERS, but events associated with permeability changes in neuronal membranes may be responsible.