POSITIVE VS NEGATIVE SCHIZOPHRENIA - A CRITICAL-EVALUATION

POSITIVE VS NEGATIVE SCHIZOPHRENIA - A CRITICAL-EVALUATION
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DOI:
10.1093/schbul/11.3.380
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发表时间:
1985-01-01
影响因子:
6.6
通讯作者:
ANDREASEN, NC
ANDREASEN, NC
中科院分区:
医学1区
文献类型:
--
作者:
ANDREASEN, NC

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对积极和消极区别的讨论往往不能解决这种区别是指症状、症状还是疾病。症状和证候在病因上是非特异性的,而疾病有特定的可识别的病理生理学或病因学。积极和消极的区别有时被讨论为一种假设,用于识别精神分裂症综合征中不同的疾病亚型。在这篇综述中,对支持这种亚型方法的证据进行了批判性的回顾,并提出了对原始假设形式的修改。
Discussion of the positive vs. negative distinction often fails to address whether this distinction refers to symptoms, syndromes, or diseases. Symptoms and syndromes are etiologically nonspecific, while diseases have a specific identifiable pathophysiology or etiology. The positive vs. negative distinction is sometimes discussed as a hypothesis for identifying discrete subtypes of disease within the schizophrenic syndrome. In this overview, the evidence supporting this approach to subtyping is critically reviewed, and modifications of the original form of the hypothesis are proposed.