Perspective on Global Measles Epidemiology and Control and the Role of Novel Vaccination Strategies.
Perspective on Global Measles Epidemiology and Control and the Role of Novel Vaccination Strategies.
复制标题
DOI：
10.3390/v9010011
复制
发表时间：
2017-01-19
期刊：
影响因子：
--
通讯作者：
Rota PA
中科院分区：
文献类型：
--
作者：
Coughlin MM;Beck AS;Bankamp B;Rota PA
麻疹是一种高度传染性的疫苗可预防的疾病。麻疹会导致全身性疾病，导致严重的免疫抑制，常常导致严重的并发症。 2010年，世界卫生大会宣布麻疹可以而且应该被根除。美洲地区已经消除了麻疹，世界卫生组织（WHO）的其余五个地区也制定了消除麻疹的目标。通过增加第一剂和第二剂含麻疹疫苗的全球覆盖率，导致全球麻疹发病率下降，并通过世卫组织全球麻疹和风疹实验室网络支持的改进基于病例的监测，取得了重大进展。改进的疫苗递送方法可能在实现消除麻疹目标方面发挥重要作用，因为这些递送方法规避了许多与皮下注射相关的后勤问题。这篇综述强调了全球麻疹流行病学的现状、新的麻疹疫苗接种策略，并描述了消除麻疹的途径。
Measles is a highly contagious, vaccine preventable disease. Measles results in a systemic illness which causes profound immunosuppression often leading to severe complications. In 2010, the World Health Assembly declared that measles can and should be eradicated. Measles has been eliminated in the Region of the Americas, and the remaining five regions of the World Health Organization (WHO) have adopted measles elimination goals. Significant progress has been made through increased global coverage of first and second doses of measles-containing vaccine, leading to a decrease in global incidence of measles, and through improved case based surveillance supported by the WHO Global Measles and Rubella Laboratory Network. Improved vaccine delivery methods will likely play an important role in achieving measles elimination goals as these delivery methods circumvent many of the logistic issues associated with subcutaneous injection. This review highlights the status of global measles epidemiology, novel measles vaccination strategies, and describes the pathway toward measles elimination.