Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process
Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process
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DOI：
10.21873/invivo.11957
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发表时间：
2020-05-01
期刊：
影响因子：
2.3
通讯作者：
Buonomo, Oreste Claudio
中科院分区：
文献类型：
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作者：
Vanni, Gianluca;Materazzo, Marco;Buonomo, Oreste Claudio
背景/目的：新冠肺炎(CoronaVirus-19，简称SARS)大流行目前正对医疗资源配置产生巨大影响。乳腺癌(BC)患者既关注BC治疗，也关注新冠肺炎。本研究旨在评估新冠肺炎传播对患者焦虑情绪的影响。患者和方法：从2020年1月16日至3月20日，我们对160例患者进行了回顾性研究。将82例可疑乳腺病变的患者分为新冠肺炎乳房手术前和新冠肺炎乳房手术后两组。将78例BC患者分为新冠肺炎治疗前和新冠肺炎治疗后两组。记录患者的年龄、婚姻状况、SBL/BC直径、BC个人和家族史、临床分期和分子亚型。记录手术拒绝(PR)和手术拒绝(SR)的原因。结果：BC和SBL分析显示治疗前特征无差异(p>；0.05)。新冠肺炎术后PR率和SR率显著高于新冠肺炎术后(P=0.0208，P=0.0065)。感染风险是新冠肺炎术后患者拒绝接受治疗的主要原因。结论：新冠肺炎相关焦虑影响患者的决策过程。
Background/Aim: Coronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19. Patients and Methods: Between the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason. Results: BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients. Conclusion: COVID-19-related anxiety could affect patients' decision-making process.