Accuracy and value of the Hemoccult test in symptomatic patients.
Accuracy and value of the Hemoccult test in symptomatic patients.
复制标题
有症状患者的血隐试验的准确性和价值。
DOI：
10.1136/bmj.286.6366.673
复制
发表时间：
1983
期刊：
影响因子：
--
通讯作者：
R. Hunt
中科院分区：
文献类型：
--
作者：
R. Leicester;A. Lightfoot;J. Millar;D. Colin;R. Hunt
粪便隐血试验被广泛提倡作为结直肠癌的筛查试验，但很少有研究表明其与结直肠疾病的常规调查方法的相关性。在一项对802例疑似结直肠疾病的症状性患者进行的前瞻性研究中，患者依从性良好（92.5%），对结直肠癌的特异性较高（85.4%）。假阳性率为8.6%（12 140例阳性结果），而22 26结肠癌的检测结果是阳性的直肠癌的假阴性率（45.4%）不应该减损其作为一个筛选试验的价值，如果适当的数字肛门直肠和直肠乙状结肠镜检查广泛实行。一个积极的潜血试验结果是一个有用的指标，需要进行全面的结肠直肠调查，包括结肠镜检查。
Hemoccult faecal occult blood testing is widely advocated as a screening test for colorectal cancer but few studies have shown its correlation with conventional methods of investigation for colorectal disease. In a prospective study of 802 symptomatic patients with suspected colorectal disease there was good patient compliance (92.5%) and a high specificity for colorectal cancer (85.4%). The false positive rate was 8.6% (12 of 140 patients with positive results), and while the test result was positive in 22 of 26 colonic cancers the false negative rate for rectal cancer (45.4%) should not detract from its value as a screening test if proper digital anorectal and proctosigmoidoscopic examination are widely practised. A positive Hemoccult test result is a useful indicator for the need to proceed to full colorectal investigation, including colonoscopy.