Gilles de la Tourette syndrome
Gilles de la Tourette syndrome
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吉尔·德拉图雷特综合症
DOI：
10.1007/978-1-4899-6768-8_24
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发表时间：
1989
影响因子：
3.4
通讯作者：
A. Friedhoff
中科院分区：
文献类型：
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作者：
A. Friedhoff
1885年，乔治·吉勒斯·德·拉·图雷特首次明确描述了这种疾病。症状包括多次抽搐，发音不当，包括咕噜声、咳嗽和淫秽词汇，通常在2至15岁之间开始。最初的症状通常是眨眼，以波动的过程进展到包括发声在内的更广泛的疾病。虽然心理后果可能是严重的，但至少在一定程度上，这是次要的，因为症状具有社会侵入性。除了一些患者的学习障碍、注意力障碍、多动、强迫、强迫和冲动行为外，这种障碍本身被认为不会产生主要的精神问题。大约40%的患者在成年早期显著改善，其余的人在一生中保持着波动的严重程度的症状。
This disorder was first definitively described in 1885 by Georges Gilles de la Tourette. Symptoms, consisting of multiple tics, inappropriate vocalizations including grunts, coughs, and obscene words, usually begin between 2 and 15 years of age. The first symptoms are often eye blinks, progressing in a fluctuating course to a more generalized disorder including vocalizations. Although the psychological consequences can be severe, this is, at least in part, secondary to the socially intrusive nature of the symptoms. The disorder itself is not believed to produce primary mental problems except for learning disabilities, attentional disturbance, hyperactivity, obsessions, compulsions, and impulsive behavior in some patients. About 40% of sufferers significantly improve in early adulthood, the remainder maintaining symptoms of fluctuating severity throughout life.