Surface Imaging by Self-propelled Nanoscale Probes
Surface Imaging by Self-propelled Nanoscale Probes
复制标题
自驱动纳米级探针的表面成像
DOI：
10.1017/s1431927602103539
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发表时间：
2002
影响因子：
2.8
通讯作者：
V. Vogel
中科院分区：
文献类型：
--
作者：
H. Hess;J. Clemmens;J. Howard;V. Vogel
引入了一种新的图像微观表面特性的方法。通过重复采集来自大量显微镜，自propell的探针在跨表面的随机路径上移动的大量显微镜，自我信号获得有关表面特性（例如地形）的信息。与确定性的线性采样相比，这些自propelled探针在统计过程中采样了表面。该方法使用微管作为探针进行了实验证明，该探针被运动蛋白动力蛋白移动。
A new approach to image microscopic surface properties is introduced. Information about surface properties such as topography is obtained by repeated acquisition of an optical signal from a large number of microscopic, self-propelled probes moving on random paths across a surface. These self-propelled probes sample the surface in a statistical process in contrast to the deterministic, linear sampling performed by a scanning probe microscope. This method is experimentally demonstrated using microtubules as probes, which are moved by the motor protein kinesin.