Time-to-Pregnancy and Associated Factors among Couples with Natural Planned Conception in Addis Ababa, Ethiopia
Time-to-Pregnancy and Associated Factors among Couples with Natural Planned Conception in Addis Ababa, Ethiopia
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DOI：
10.29063/ajrh2018/v22i3.4
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发表时间：
2018-09-01
影响因子：
1
通讯作者：
Kebede, Eskinder
中科院分区：
文献类型：
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作者：
Kassa, Eyasu Mesfin;Kebede, Eskinder
夫妇的等待怀孕时间（TTP）与生育能力密切相关。TTP的知识有助于临床医生对低生育力/不孕症进行个性化护理。已发表的关于TTP的研究在非洲背景下非常有限。这项横断面研究评估了埃塞俄比亚阿迪斯自然计划受孕夫妇的TTP及其相关因素。数据收集采访了1150名孕妇的代表性样本。平均和中位TTP分别为6.4（+/- 9.4）和3.0个月。只有11.8%（136/1，150）在尝试的第一个月内成功怀孕。大多数，81.7%（938/1 150），在12个月内怀孕。25-29岁年龄组的生育力低下（TTP超过12个月）的几率最低（AOR 0.37; 95%CI 0.20-0.70）。每周工作超过60小时（AOR 1.87; 95% CI 1.02-3.42），每天喝3杯以上咖啡（AOR 1.87; 95% CI 1.02-3.42），其伴侣咀嚼阿拉伯茶（AOR 1.66; 95% CI 1.06-2.60）的女性具有显著更高的亚生殖力几率。首次妊娠前使用埋植避孕药（AOR 0.28; 95% CI 0.15-0.51）和避孕药（AOR 0.53; 95% CI 0.32-0.89）具有显著较低的生育力低下几率。这项研究没有考虑咀嚼阿拉伯茶的数量、持续时间和频率，因此其对繁殖力/TTP的剂量依赖性影响需要进一步研究。
Waiting time-to-pregnancy (TTP) of couples is closely related to fecundability. Knowledge on TTP helps clinicians to individualize care for sub-fertility/infertility. Published studies on TTP are very limited in African setting. This cross-sectional study assessed TTP and associated factors among couples with natural planned conception in Addis Ababa, Ethiopia. Data was collected interviewing a representative sample of 1150 pregnant women. The mean and median TTPs were 6.4 (+/- 9.4) and 3.0 months respectively. Only 11.8% (136/1,150) achieved pregnancy in the first month of attempt. Majority, 81.7% (938/1,150), achieved pregnancy by 12 months. The odds of sub-fecundity (TTP more than 12 months) was lowest in age group of 25-29 years (AOR 0.37; 95% CI 0.20-0.70). Women working more than 60 hours/week (AOR 1.87; 95% CI 1.02-3.42), who drink more than 3 cups of coffee/day (AOR 1.87; 95% CI 1.02-3.42), and whose partners chew khat (AOR 1.66; 95% CI 1.06-2.60) had significantly higher odds of sub-fecundity. Use of contraceptive implants (AOR 0.28; 95% CI 0.15-0.51) and pills (AOR 0.53; 95% CI 0.32-0.89) before the index pregnancy had significantly lower odds of sub-fecundity. This study did not consider amount, duration and frequency of khat chewing, hence its dose dependent effect on fecundability/TTP needs further investigation.