Agminated atypical melanocytic nevus associated with Langerhans cell histiocytosis*
Agminated atypical melanocytic nevus associated with Langerhans cell histiocytosis*
复制标题
与朗格汉斯细胞组织细胞增多症相关的聚集性非典型黑素细胞痣*
DOI：
10.1590/abd1806-4841.20198620
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发表时间：
2019
影响因子：
1.7
通讯作者：
G. Solís
中科院分区：
文献类型：
--
作者：
Ehekatzin Arturo Carreño;S. Hernández;E. Guevara;G. Solís
集束状痣是指在有限的皮肤区域内聚集的多发性痣，在文献中很少报道。本文报告一例10岁女性患者，有朗格汉斯细胞组织细胞增生症病史，在腰部和腹股沟区域出现多发性痣。在组织病理学研究中，报告了一例不典型的黑色素细胞痣。伍德的灯检查排除了溢出痣的存在，并达到了集束状痣的诊断。这种类型的痣与朗格汉斯细胞组织细胞增生症的关联是罕见的，在索引文献中只发现了四个病例。这种联系的原因尚不清楚，因此提出了一种关于其起源的新理论。
Agminated nevus refers to the presence of multiple nevi grouped in a circumscribed skin area; it is rarely reported in the literature. This report presents the case of a 10-year-old female patient with a history of Langerhans cell histiocytosis, who presents multiple nevi in the lumbar and inguinal region. In the histopathological study, an atypical melanocytic nevus was reported. Wood’s lamp examination discarded the presence of nevus spilus, and the diagnosis of agminated nevus was reached. The association of this type of nevus with Langerhans cell histiocytosis is rare, and only four cases were found reported in the indexed literature. The reason for this association is unknown, thus a new theory about its origin is presented here.