A randomized trial of postoperative five-versus three-drug chemotherapy after mastectomy: a Cancer and Leukemia Group B (CALGB) study.

A randomized trial of postoperative five-versus three-drug chemotherapy after mastectomy: a Cancer and Leukemia Group B (CALGB) study.
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乳房切除术后五药与三药化疗的随机试验：癌症和白血病 B 组 (CALGB) 研究。

DOI：
10.1007/978-3-642-81685-7_28
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发表时间：
1982
期刊：
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
影响因子：
--
通讯作者：
Glidewell,OJ
Glidewell,OJ
中科院分区：
--
文献类型：
--
作者：
Weiss,RB;Tormey,DC;Holland,F;Weinberg,VE;Lesnick,G;Perloff,M;Falkson,G;Glidewell,OJ

文献摘要

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癌症和白血病B组(CALB)对乳腺癌患者进行了一项随机的辅助化疗研究，这些患者在乳房切除时有腋窝淋巴结受累。将五药疗法(CMFVP)与三药疗法(CMF)进行比较。对于有三个以上受累结节的患者，与CMF方案相比，CMFVP方案的无瘤生存期显著延长。
The Cancer and Leukemia Group B (CALB) has conducted a randomized study of adjuvant chemotherapy in patients with breast cancer who have involved axillary nodes at the time of mastectomy. Five-drug treatment (CMFVP) was compared with three-drug treatment (CMF). For patients with more than three involved nodes, the CMFVP regimen produced a significantly prolonged disease-free survival in comparison to the CMF regimen.