Exercise and restless legs syndrome: A randomized controlled trial

Exercise and restless legs syndrome: A randomized controlled trial
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DOI:
10.3122/jabfm.19.5.487
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发表时间:
2006-09-01
影响因子:
2.9
通讯作者:
Bailey, Beth
Bailey, Beth
中科院分区:
医学3区
文献类型:
--
作者:
Aukerman, Melissa McManama;Aukerman, Douglas;Bailey, Beth

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背景和目的:不宁腿综合征(RLS)是一种常见的、诊断不足的神经运动障碍,其病因尚未确定。不宁腿综合征的主要治疗方法是药物治疗。迄今为止,还没有随机对照试验检验运动计划对 RLS 症状的有效性。方法:研究参与者 (N = 41) 被随机分配到运动组或对照组。 28 名参与者(平均年龄 53.7 岁;39% 为男性)愿意开始为期 12 周的试验。运动组接受每周3天的有氧运动和下半身抗阻训练的调理计划。在试验开始时以及第 3、6、9 和 12 周时,通过国际 RLS 研究组 (IRLSSG) 严重程度量表和不宁腿严重程度顺序量表评估不宁腿症状。 结果:23 名参与者完成了试验。 12 周结束时,与对照组 (N = 12) 相比,运动组 (N = 11) 的症状有显着改善(IRLSSG 严重程度量表 P = 0.001,P
Background and Objectives: Restless legs syndrome (RLS) is a common, underdiagnosed neurological movement disorder of undetermined etiology. The primary treatments for restless legs syndrome are pharmacological. To date, no randomized controlled trials have examined the effectiveness of an exercise program on the symptoms of RLS.Methods: Study participants (N = 41) were randomized to either exercise or control groups. 28 participants ( average age 53.7; 39% males) were available and willing to begin the 12-week trial. The exercise group was prescribed a conditioning program of aerobic and lower-body resistance training 3 days per week. Restless legs symptoms were assessed by the International RLS Study Group (IRLSSG) severity scale and an ordinal scale of RLS severity at the beginning of the trial, and at 3, 6, 9, and 12 weeks.Results: Twenty-three participants completed the trial. At the end of the 12 weeks, the exercise group ( N = 11) had a significant improvement in symptoms compared with the control group ( N = 12) ( P =.001 for the IRLSSG severity scale and P